JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / Monoclonal Antibodies

Anti-RENT1/hUPF1 Antibody Picoband® (monoclonal, 11E7)

SKU : BHA21002590

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

Boster

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	M00900, M00900-10ug, M00900-Biotin, M00900-Cy3, M00900-Dylight488, M00900-Dylight550, M00900-Dylight594, M00900-FITC, M00900-HRP, M00900-APC, M00900-PE, M00900-iFluor647, M00900-carrier-free
Alternative Names	UPF1 regulator of nonsense transcripts homolog (yeast)
Background	Regulator of nonsense transcripts 1 is a protein that in humans is encoded by the UPF1 gene. This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. And this protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alteative splicing results in multiple transcript variants.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-RENT1/hUPF1 Antibody Picoband® (monoclonal, 11E7) catalog # M00900. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	RNA-dependent helicase and ATPase required for nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation; its phosphorylation
Host	Mouse
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human RENT1/hUPF1, identical to the related mouse and rat sequences.
Isotype	Mouse IgG2b
Molecular Weight	130 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	ATP dependent helicase RENT1 antibody; ATP-dependent helicase RENT1 antibody; Delta helicase antibody; FLJ43809 antibody; FLJ46894 antibody; HUPF 1 antibody; hUpf1 antibody; KIAA0221 antibody; Nonsense mRNA reducing factor 1 antibody; NORF 1 antibody; NORF1 antibody; pNORF 1 antibody; pNORF1 antibody; Regulator of nonsense transcripts 1 antibody; RENT 1 antibody; RENT1 antibody; RENT1_HUMAN antibody; Smg 2 antibody; Smg 2 homolog nonsense mediated mRNA decay factor antibody; UP Frameshift 1 antibody; Up frameshift mutation 1 homolog (S. cerevisiae) antibody; Up frameshift mutation 1 homolog antibody; Up frameshift suppressor 1 homolog antibody; Up-frameshift suppressor 1 homolog antibody; UPF 1 antibody; UPF 1 regulator of nonsense transcripts homolog antibody; upf1 antibody; UPF1 regulator of nonsense transcripts homolog antibody; Yeast Upf1p homolog antibody
Tissue Specificity	Ubiquitous.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	Q92900
Gene Id	5976
Gene Name	UPF1
Clone No	Clone: 11E7
Subcellular Location	Nucleus. Cytoplasm. P-body.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 2ug/ml, Human<br>

Reference	1. "Entrez Gene: UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)".<br /><br />2. Applequist SE, Selg M, Raman C, Jack HM (March 1997). "Cloning and characterization of HUPF1, a human homolog of the Saccharomyces cerevisiae nonsense mRNA-reducing UPF1 protein". Nucleic Acids Res 25 (4): 81421.<br /><br />3. Perlick HA, Medghalchi SM, Spencer FA, Kendzior RJ Jr, Dietz HC (November 1996). "Mammalian orthologues of a yeast regulator of nonsense transcript stability". Proc Natl Acad Sci U S A 93 (20): 1092832.

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002590-1	M00900	-	100 ug	$370		Add to Cart
BHA21002590-2	M00900-10ug	Sample	10 ug	$99		Add to Cart
BHA21002590-3	M00900-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002590-4	M00900-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002590-5	M00900-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002590-6	M00900-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002590-7	M00900-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002590-8	M00900-FITC	FITC	100 ug	$570		Add to Cart
BHA21002590-9	M00900-HRP	HRP	100 ug	$570		Add to Cart
BHA21002590-10	M00900-APC	APC	100 ug	$670		Add to Cart
BHA21002590-11	M00900-PE	PE	100 ug	$670		Add to Cart
BHA21002590-12	M00900-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002590-13	M00900-carrier-free	carrier-free	100 ug	$370		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.