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Home / Primary Antibodies / Monoclonal Antibodies

Anti-RAB11B Antibody Picoband® (monoclonal, 6C5)

SKU : BHA21002497

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Mfr.No.	M04526, M04526-10ug, M04526-Biotin, M04526-Cy3, M04526-Dylight488, M04526-Dylight550, M04526-Dylight594, M04526-FITC, M04526-HRP, M04526-APC, M04526-PE, M04526-iFluor647, M04526-carrier-free
Alternative Names	RAB11B,member RAS oncogene family
Background	Ras-related protein Rab-11B is a protein that in humans is encoded by the RAB11B gene. It is mapped to 19p13.2. The Ras superfamily of small GTP-binding proteins, which includes the Ras, Ral, Rho, Rap, and Rab families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-RAB11B Antibody Picoband® (monoclonal, 6C5) catalog # M04526. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	The small GTPases Rab are key regulators of intracellular membrane trafficking,from the formation of transport vesicles to their fusion with membranes.Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to me
Host	Mouse
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human RAB11B, which shares 97.4% and 100% amino acid (aa) sequence identity with mouse and rat RAB11B, respectively.
Isotype	Mouse IgG2b
Molecular Weight	24 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Ras-related protein Rab-11B;GTP-binding protein YPT3; RAB11B;YPT3
Tissue Specificity	Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q15907
Gene Id	9230
Gene Name	RAB11B
Clone No	Clone: 6C5
Subcellular Location	Recycling endosome membrane;Lipid-anchor;Cytoplasmic side.Cytoplasmic vesicle,secretory vesicle,synaptic vesicle membrane;Lipid-anchor;Cytoplasmic side.Cytoplasmic vesicle,phagosome membrane;Lipid-anchor;Cytoplasmic side.Recruited to phagosomes containing S.aureus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 2ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Gross, M. B. Personal Communication. Baltimore, Md. 7/25/2014.<br /><br />2. Lamers, I. J. C., Reijnders, M. R. F., Venselaar, H., Kraus, A., DDD Study, Jansen, S., de Vries, B. B. A., Houge, G., Gradek, G. A., Seo, J., Choi, M., Chae, J.-H., and 11 others. Recurrent de novo mutations disturbing the GTP/GDP binding pocket of RAB11B cause intellectual disability and a distinctive brain phenotype. Am. J. Hum. Genet. 101: 824-832, 2017.<br /><br />3. Zhu, A. X., Zhao, Y., Flier, J. S. Molecular cloning of two small GTP-binding proteins from human skeletal muscle. Biochem. Biophys. Res. Commun. 205: 1875-1882, 1994.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002497-1	M04526	-	100 ug	$370		Add to Cart
BHA21002497-2	M04526-10ug	Sample	10 ug	$99		Add to Cart
BHA21002497-3	M04526-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002497-4	M04526-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002497-5	M04526-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002497-6	M04526-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002497-7	M04526-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002497-8	M04526-FITC	FITC	100 ug	$570		Add to Cart
BHA21002497-9	M04526-HRP	HRP	100 ug	$570		Add to Cart
BHA21002497-10	M04526-APC	APC	100 ug	$670		Add to Cart
BHA21002497-11	M04526-PE	PE	100 ug	$670		Add to Cart
BHA21002497-12	M04526-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002497-13	M04526-carrier-free	carrier-free	100 ug	$370		Add to Cart

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