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Home / Primary Antibodies / Monoclonal Antibodies

Anti-PTBP2 Picoband® Antibody (monoclonal, 13D11)

SKU : BHA21003163

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Mfr.No.	M05020-2, M05020-2-10ug, M05020-2-Biotin, M05020-2-Cy3, M05020-2-Dylight488, M05020-2-Dylight550, M05020-2-Dylight594, M05020-2-FITC, M05020-2-HRP, M05020-2-APC, M05020-2-PE, M05020-2-iFluor647, M05020-2-carrier-free
Alternative Names	cofilin 2
Background	Polypyrimidine tract binding protein 2, also known as PTBP2, is a protein which in humans is encoded by the PTBP2 gene. It is mapped to 1p21.3. The protein encoded by this gene binds to intronic polypyrimidine clusters in pre-mRNA molecules and is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein (PTB) but most of its isoforms are expressed primarily in the brain. Alteative splicing results in multiple transcript variants.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-PTBP2 Picoband® Antibody (monoclonal, 13D11) catalog # M05020-2. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. Its F-actin depolymerization activity is regulated by association with CSPR3. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the m
Host	Mouse
Immunogen Region	E.coli-derived human PTBP2 recombinant protein (Position: M1-A504).
Isotype	Mouse IgG2a
Molecular Weight	57-60 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Cofilin-2; Cofilin, muscle isoform; CFL2
Tissue Specificity	Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Uniprot	Q9UKA9
Gene Id	58155
Gene Name	PTBP2
Clone No	Clone: 13D11
Subcellular Location	Cytoskeleton. Nucleus matrix.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, ICC, IF, Flow Cytometry
Description	Weste blot, 0.25-0.5ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Makeyev, E. V., Zhang, J., Carrasco, M. A., Maniatis, T. The microRNA miR-124 promotes neuronal differentiation by triggering brain-specific alteative pre-mRNA splicing. Molec. Cell 27: 435-448, 2007. <br /><br />2. Rahman, L., Bliskovski, V., Kaye, F. J., Zajac-Kaye, M. Evolutionary conservation of a 2-kb intronic sequence flanking a tissue-specific alteative exon in the PTBP2 gene. Genomics 83: 76-84, 2004.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003163-1	M05020-2	-	100 ug	$370		Add to Cart
BHA21003163-2	M05020-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21003163-3	M05020-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003163-4	M05020-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003163-5	M05020-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003163-6	M05020-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003163-7	M05020-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003163-8	M05020-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21003163-9	M05020-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21003163-10	M05020-2-APC	APC	100 ug	$670		Add to Cart
BHA21003163-11	M05020-2-PE	PE	100 ug	$670		Add to Cart
BHA21003163-12	M05020-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003163-13	M05020-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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