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Home / Primary Antibodies / Monoclonal Antibodies

Anti-PSMA-Anti-CD3 IgG format Bispecific Antibody

SKU : BHA18200074

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BPS Bioscience

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Mfr.No.	101242-1
Clonality	Monoclonal (Bispecific)
Description	Anti-PSMA-Anti-CD3 IgG format bispecific antibody is a purified recombinant human bispecific antibody with T cell Engager. This bispecific antibody has been tested for specific activity in the functional reporter assay using NFAT-luc reporter Jurkat cell line (BPS Bioscience #60621) in the presence of PSMA-CHO cells (BPS Bioscience #79641-H).PSMA (Prostate-Specific Membrane antigen), also known as FLOH1 (folate hydrolase 1) and NAALADase I (N-acetyl-L-aspartyl-L-glutamate peptidase I) is a transmembrane protein highly expressed in the intestine, the prostate, and the nervous system. The protein is a glutamate carboxypeptidase involved in folate metabolism and may be involved in pathological conditions such as hyperhomocysteinemia (intestine) and glutamate toxicity (nervous system). PSMA is overexpressed in prostate cancer cells and is the target of an increasing number of diagnostic and therapeutic approaches used for the treatment of prostate cancer. assay conditions: See datasheet for detailed information
Formulation	8 mM phosphate, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol
Molecular Weight	~150 kDa (Heavy Chain: 50 kDa; Light Chain: 24 kDa)
Species	Human
Synonyms	PSMA, Prostate-Specific Membrane antigen, FOLH, FOLH1, folate hydrolase 1, NAALAD1, NAALADase I, N-acetyl-L-aspartyl-L-glutamate peptidase I, PSM, FGCP, Glutamate carboxypeptidase, GCP2, membrane glutamate carboxypeptidase, mGCP, GCPII, 101242-1, 101242
Note	Avoid freeze/thaw cycles.

Format	Aqueous buffer solution
Purification	Protein A affinity purification of the IgG-tag protein from HEK293 cells.
Purity	>=90%
Shipping Temperature	-80°C (dry ice)
Storage Stability	At least 12 months at -80°C.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA18200074	101242-1	50 ug	$429		Add to Cart

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