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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Proteasome 20S beta 7/PSMB7 Antibody Picoband® (monoclonal, 3H6C8)

SKU : BHA21004834

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Mfr.No.	M08095-2, M08095-2-10ug, M08095-2-Biotin, M08095-2-Cy3, M08095-2-Dylight488, M08095-2-Dylight550, M08095-2-Dylight594, M08095-2-FITC, M08095-2-HRP, M08095-2-APC, M08095-2-PE, M08095-2-iFluor647, M08095-2-carrier-free
Alternative Names	chaperonin containing TCP1 subunit 3
Background	Proteasome subunit beta type-7 as known as 20S proteasome subunit beta-2 is a protein that in humans is encoded by the PSMB7 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Proteasome 20S beta 7/PSMB7 Antibody Picoband® (monoclonal, 3H6C8) catalog # M08095-2. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vi
Host	Mouse
Immunogen Region	E.coli-derived human Proteasome 20S beta 7/PSMB7 recombinant protein (Position: D17-S277).
Isotype	IgG2b
Molecular Weight	25 kDa
Reactivity	Human, Monkey, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	T-complex protein 1 subunit gamma; TCP-1-gamma; CCT-gamma; hTRiC5; CCT3; CCTG; TRIC5
Tissue Specificity	Ubiquitously expressed with highest levels in spleen, thymus and immature brain.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	Q99436
Gene Id	5695
Gene Name	PSMB7
Clone No	Clone: 3H6C8
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry
Description	Weste blot, 0.25-0.5 ug/ml, Human, Monkey, Mouse, Rat Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human

Reference	1. Coux, O., Tanaka, K., Goldberg, A. L. Structure and functions of the 20S and 26S proteasomes. Ann. Rev. Biochem. 65: 801-847, 1996. 2. Hisamatsu, H., Shimbara, N., Saito, Y., Kristensen, P., Hendil, K. B., Fujiwara, T., Takahashi, E., Tanahashi, N., Tamura, T., Ichihara, A., Tanaka, K. Newly identified pair of proteasomal subunits regulated reciprocally by interferon gamma. J. Exp. Med. 183: 1807-1816, 1996.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004834-1	M08095-2	-	100 ug	$370		Add to Cart
BHA21004834-2	M08095-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21004834-3	M08095-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004834-4	M08095-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004834-5	M08095-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004834-6	M08095-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004834-7	M08095-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004834-8	M08095-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21004834-9	M08095-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21004834-10	M08095-2-APC	APC	100 ug	$670		Add to Cart
BHA21004834-11	M08095-2-PE	PE	100 ug	$670		Add to Cart
BHA21004834-12	M08095-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004834-13	M08095-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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