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Home / Primary Antibodies / Monoclonal Antibodies

Anti-PD-L1 (CD274) Neutralizing Antibody

SKU : BHA18200007

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BPS Bioscience

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Mfr.No.	71213
Clonality	Monoclonal
Description	Neutralizing recombinant chimeric murine/human monoclonal antibody recognizing the extracellular domain of PD-L1 and blocking the binding of PD-L1 to PD-1. This antibody has been shown to cross-react with mouse PD-L1. No other species have been tested. assay conditions: 11.5 nM using PD-1:PD-L1(Biotinylated)Inhibitor Screening Assay Kit (BPS Bioscience,Cat. #72003) and human PD-1 and PD-L1. 1.8nM using mouse PD-L1 and mouse PD-1(Biotinylated). Endotoxin level < 1 EU/ ug. Specific activity: IC50 = 11.5 nM (human PD-L1) 1.8 nM (mouse PD-L1)
Formulation	8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol
Isotype	IgG1kappa
Molecular Weight	50 and 25 kDa for the heavy and light chains, respectively (150 kDa).
Species	Human/Mouse
Synonyms	Programmed Cell Death 1 Ligand 1, PDL1, PD-L1, B7 homolog 1, B7H1, B7-H1, CD274, PDCD1L1
Tag	None
Note	Avoid freeze/thaw cycles. Store diluted antibody with carrier protein (BSA 0.1 - 0.5%) at 4°C, stable for 2 weeks.

Uniprot	Q9NZQ7

Format	Aqueous buffer solution.
Purification	Protein A affinity chromatographyfrom HEK293 supernatants.
Shipping Temperature	-80°C (dry ice)
Storage Stability	Stable for at least 12 months at-80°C.

Product Manual	Datasheet

Reference	1. Freeman, G.J., et al., J. Exp. Med. 2000; 192(7): 1027-1034. 2. Dong, H., et al., Nat. Med. 1999; 5(12): 1365-1369.

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SKU	Supplier No.	Size	Your price	Quantity
BHA18200007	71213	100 ug	$555.50		Add to Cart

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