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Home / Primary Antibodies / Monoclonal Antibodies

Anti-PD-1 Neutralizing Antibody

SKU : BHA18200003

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BPS Bioscience

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Mfr.No.	71120
Clonality	Monoclonal
Description	Neutralizing recombinant murine/human chimeric antibody recognizing the PD-L1/PD-L2 binding region of human PD-1. This antibody does not cross-react with mouse PD-1, but does cross-react with monkey (M. fascicularis) PD-1. It has not been tested with other species. assay conditions: Antibody was added to PD-1(Biotinylated):PD-L1 or PD-1(Biotinylated):PD-L2 binding assay at various concentrations. Assay was performed according to the protocol in BPS Cat. #72005 or #72006, respectively. Specific activity: IC50 = 1.2 nM using the PD-1(Biotinylated):PD-L1 Inhibitor Screening Assay Kit (BPS Cat. #72005). IC50 = 4.7 nM using the PD-1(Biotinylated):PD-L2 Inhibitor Screening Assay Kit.
Formulation	40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Isotype	IgG1
Molecular Weight	50 and 25 kDa for the heavy and light chains, respectively (150 kDa).
Species	Human/Mouse
Synonyms	Anti-PD1
Tag	none
Note	Avoid freeze/thaw cycles.

Uniprot	Q15116

Format	Aqueous buffer solution
Purification	Protein A affinity chromatography from HEK293 supernatants.
Shipping Temperature	-80°C (dry ice)
Storage Stability	Stable for at least 12 months at -80°C. Store diluted antibody with carrier protein (BSA 0.1 - 0.5%) at 4°C, stable for 2 weeks.

Product Manual	Datasheet

Reference	1. Shinohara, T., et al., Genomics. 1994 Oct;23(3):704-6.2. James, E.S., et al., Genes Immun. 2005 Aug;6(5):430-7.

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SKU	Supplier No.	Size	Your price	Quantity
BHA18200003	71120	100 ug	$511.50		Add to Cart

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