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Home / Primary Antibodies / Monoclonal Antibodies

Anti-PCSK9 antibody(DMC222), IgG1 Chimeric mAb

SKU : BHA18100112

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DIMA Biotechnology

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Mfr.No.	DMC100222
Background	This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutIVe branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutIVely secreted as an inactIVe protease into the eXtracellular matriX and trans-Golgi network. It is eXpressed in lIVer, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. AlternatIVe splicing results in multiple transcript variants.
Clonality	Monoclonal
Host	Rabbit
Isotype	Human IgG
Reactivity	Human
Solubility	ELISA 1/5000-10000;Flow Cyt 1/100
Synonyms	FH3, FHCL3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9
Usage	Research use only

Form	Powder
Purification	Purified from cell culture supernatant by affinity chromatography
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Applications	ELISA,Flow Cyt

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SKU	Supplier No.	Size	Your price	Quantity
BHA18100112	DMC100222	100 ug	$398		Add to Cart
BHA18100112	DMC100222	10 ug	$60		Add to Cart

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