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Home / Primary Antibodies / Monoclonal Antibodies

Anti-p21/WAF1

SKU : BHA15100173

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Mfr.No.	AM434-5M
Clonality	Monoclonal
Description	The p21/WAF1 a cyclin-dependent kinase inhibitor protein encoded by p21/WAF1 gene and and one of the key p53 regulated gene product and it mediates cell cycle growth arrest in the absence of p53 expression and also plays a significant role of a tumor suppressor in cancer. It induces cell growth arrest due to cyclin dependent kinase inhibition activity, and maintains G2 cell cycle arrest by inhibiting the interaction of PCNA with Cdc25C and other activated protein kinases. Recent studies show that p21 may possibly act as an oncogene, because it inhibits apoptosis in the absence of p53 and induce cell proliferation in some tumors. These studies bring out the "antagonistic duality" of p21, since it shows both the pro oncogenic and anticancer properties at the same time(2). New data indicates and challenges already established proto-oncogene and anti oncogenes
Host	Mouse
Isotype	IgG1
Reactivity	Human
Species	Mouse

Clone No	4D10
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:10-20

Product Manual	Datasheet SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
AM434-5M	AM434-5M	6 mL	$200		Add to Cart
AM434-10M	AM434-10M	100 tests - i6000	$366		Add to Cart
AX434-50D	AX434-50D	50 tests - Xmatrx	$208		Add to Cart
AX434-YCD	AX434-YCD	160 tests - Xmatrx	$574		Add to Cart
MU434-UC	MU434-UC	1ml Conc	$305		Add to Cart
MU434-5UC	MU434-5UC	0.5ml Conc	$217		Add to Cart

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