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Home / Primary Antibodies / Monoclonal Antibodies

Anti-p19INK4d Cdkn2d Antibody (Monoclonal, DCS-100)

SKU : BHA21006545

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Mfr.No.	MA1075
Alternative Names	Cyclin-dependent kinase 4 inhibitor D
Background	Cyclins are important in regulating the cell cycle through their formation of enzymatic complexes with various cyclin-dependent kinases. P19 (INK4d) also kowns as cyclin-dependent kinase inhibitor 2D, is one of the novel members of the mouse INK4 gene family. Okuda et al. (1995) described the cloning of the human INK4d gene (CDKN2D). The predicted 166-amino acid protein is 86% identical to the mouse protein and about 45% identical to other human INK4 family members.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-p19INK4d Cdkn2d Antibody (Monoclonal, DCS-100) catalog # MA1075. Tested in IHC, ICC, WB applications. This antibody reacts with Human.
Function	Interacts strongly with CDK4 and CDK6 and inhibits them. .
Host	Mouse
Immunogen Region	Recombinant human p19INK4d.
Isotype	Mouse IgG1
Molecular Weight	18 kDa
Reactivity	Human
Reconstitution	Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Cyclin-dependent kinase 4 inhibitor D;p19-INK4d;Cdkn2d;
Tissue Specificity	Expressed in spleen, liver and lung. Not detected in kidney, colon, stomach or brain. .
Note	Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Uniprot	Q60773
Gene Id	Human(1032), Mouse(12581), Rat(494444)
Gene Name	CDKN2D
Clone No	Clone: DCS-100
Sequence	Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.
Subcellular Location	Nucleus . Cytoplasm .

Concentration	Adding 1 ml of PBS buffer will yield a concentration of 100 ug/ml.
Form	Lyophilized
Purification	Ascites
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, ICC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 1-2ug/ml, Human, By Heat <br>Immunocytochemistry , 1ug/ml, Human, -<br>Weste blot, 0.5-1ug/ml, Human<br>

Reference	1. Hirai, H.; Roussel, M. F.; Kato, J.-Y.; Ashmun, R. A.; Sherr, C. J. : Novel INK4 proteins, p19 and p18, are specific inhibitors of cyclin D-dependent kinases CDK4 and CDK6. Molec. Cell. Biol. 15: 2672-2681, 1995. <br /><br />2. tsuzaki, Y.; Miyazawa, K.; Yokota, T.; Hitomi, T.; Yamagishi, H.; Sakai, T. : Molecular cloning and characterization of the human p19(INK4d) gene promoter. FEBS Lett. 517: 272-276, 2002.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006545-1	MA1075	-	100 ug	$370		Add to Cart

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