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Home / Primary Antibodies / Monoclonal Antibodies

Anti-P-Cadherin-3 CDH3-Antibody Picoband® (monoclonal, 3C9)

SKU : BHA21002603

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Mfr.No.	M03353, M03353-10ug, M03353-Biotin, M03353-Cy3, M03353-Dylight488, M03353-Dylight550, M03353-Dylight594, M03353-FITC, M03353-HRP, M03353-APC, M03353-PE, M03353-iFluor647, M03353-carrier-free
Alternative Names	cadherin 3, type 1, P-cadherin (placental)
Background	Cadherins, such as CDH3, are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion. Cadherin-3 is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-P-Cadherin-3 CDH3-Antibody Picoband® (monoclonal, 3C9) catalog # M03353. Tested in IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Host	Mouse
Immunogen Region	E. coli-derived human P cadherin recombinant protein (Position: Q126-H336).
Isotype	Mouse IgG2b
Molecular Weight	120 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Cadherin-3; Placental cadherin; P-cadherin; CDH3; CDHP
Tissue Specificity	Expressed in some normal epithelial tissues and in some carcinoma cell lines.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	P22223
Gene Id	1001
Gene Name	CDH3
Clone No	Clone: 3C9
Subcellular Location	Cell membrane. Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IF, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 2ug/ml, Human

Reference	1. Kaupmann K, Becker-Follmann J, Scherer G, Jockusch H, Starzinski-Powitz A (Dec 1992). "The gene for the cell adhesion molecule M-cadherin maps to mouse chromosome 8 and human chromosome 16q24.1-qter and is near the E-cadherin (uvomorulin) locus in both species". Genomics 14 (2): 48890.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002603-1	M03353	-	100 ug	$370		Add to Cart
BHA21002603-2	M03353-10ug	Sample	10 ug	$99		Add to Cart
BHA21002603-3	M03353-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002603-4	M03353-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002603-5	M03353-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002603-6	M03353-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002603-7	M03353-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002603-8	M03353-FITC	FITC	100 ug	$570		Add to Cart
BHA21002603-9	M03353-HRP	HRP	100 ug	$570		Add to Cart
BHA21002603-10	M03353-APC	APC	100 ug	$670		Add to Cart
BHA21002603-11	M03353-PE	PE	100 ug	$670		Add to Cart
BHA21002603-12	M03353-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002603-13	M03353-carrier-free	carrier-free	100 ug	$370		Add to Cart

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