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Home / Primary Antibodies / Monoclonal Antibodies

Anti-P-Cadherin-3 CDH3-Antibody (Monoclonal, CH-19)

BHA21006549
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Tel
+1 866.986.9598
Email
[email protected]
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Uniprot F1LMI3
Gene Id Human(999), Mouse(12550), Rat(83502), Human(1000), Mouse(12558), Rat(83501), Human(1001), Mouse(12560), Rat(116777)
Gene Name CDH1; CDH2; CDH3
Clone No Clone: CH-19
Sequence Contains 5 cadherin domains.
Subcellular Location CDH1: Cell junction. Cell membrane; Single-passtype I membrane protein. Endosome. Golgi apparatus, trans-Golginetwork. Note: Colocalizes with DLGAP5 at sites of cell-cellcontact in intestinal epithelial cells. Anchored to actinmicrofilaments through association with alpha-, beta- and gamma-catenin. Sequential proteolysis induced by apoptosis or calciuminflux, results in translocation from sites of cell-cell contactto the cytoplasm. Colocalizes with RAB11A endosomes during itstransport from the Golgi apparatus to the plasma membrane.|Cdh1: Cell junction. Cell membrane; Single-passtype I membrane protein. Endosome Golgi apparatus,trans-Golgi network Note: Colocalizes with DLGAP5 atsites of cell-cell contact in intestinal epithelial cells.Anchored to actin microfilaments through association with alpha-,beta- and gamma-catenin. Sequential proteolysis induced byapoptosis or calcium influx, results in translocation from sitesof cell-cell contact to the cytoplasm. Colocalizes with RAB11Aendosomes during its transport from the Golgi apparatus to theplasma membrane (By similarity). |Cdh1: Cell junction. Cell membrane; Single-passtype I membrane protein. Endosome Golgi apparatus,trans-Golgi network Note: Colocalizes with DLGAP5 atsites of cell-cell contact in intestinal epithelial cells.Anchored to actin microfilaments through association with alpha-,beta- and gamma-catenin. Sequential proteolysis induced byapoptosis or calcium influx, results in translocation from sitesof cell-cell contact to the cytoplasm. Colocalizes with RAB11Aendosomes during its transport from the Golgi apparatus to theplasma membrane (By similarity). |CDH2: Cell membrane; Single-pass type I membraneprotein.|Cdh2: Cell membrane; Single-pass type I membraneprotein.|Cdh2: Cell membrane |CDH3: Cell membrane; Single-pass type I membraneprotein.|Cdh3: Cell membrane; Single-pass type I membraneprotein.
Concentration Adding 1 ml of PBS buffer will yield a concentration of 100 ug/ml.
Form Lyophilized
Purification Ascites
Storage Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Applications IHC, WB
Description Immunohistochemistry (Paraffin-embedded Section), 2-4ug/ml, Human, mouse, rat, rabbit, chicken, snake., By Heat <br>Weste blot, 1-2ug/ml, Human, mouse, rat, rabbit, chicken, snake.<br>
Reference 1. Togashi, H.; Abe, K.; Mizoguchi, A.; Takaoka, K.; Chisaka, O.; Takeichi, M. : Cadherin regulates dendritic spine morphogenesis. Neuron 35: 77-89, 2002. <br /><br />2. Chalmers, I. J.; Hofler, H.; Atkinson, M. J. : Mapping of a cadherin gene cluster to a region of chromosome 5 subject to frequent allelic loss in carcinoma. Genomics 57: 160-163, 1999.<br /><br />
Combination SKU Supplier No. Conjugation Size Your price Quantity
BHA21006549-1 MA1079 - 100 ug $370
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