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Home / Primary Antibodies / Monoclonal Antibodies

Anti-NKX3.1

SKU : BHA15100426

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BioGenex Laboratories

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Mfr.No.	AMA55-5M
Clonality	Monoclonal
Description	The NKX3.1 gene is located on chromosome 8p21.2, whose expression is predominantly localized to prostate epithelium. The NKX3.1 protein acts as a nuclear transcription factor that has a critical function in prostate development and tumor suppression, and is a negative regulator of epithelial cell growth in prostate tissue. Apart from prostate epithelium, NKX3.1 is found in testis, ureter, and pulmonary bronchial mucous glands. NKX3.1 is a highly sensitive and specific marker for prostate adenocarcinoma in line with other prostate markers like Prostate Specific Antigen (PSA) and Prostein (p501S), particularly useful in low differentiated tumors where PSA and/or Prostein may be weakly expressed or lost. This suggests that immunohistochemical staining of NKX3.1, along with other prostate-restricted markers, may be valuable for the definitive determination of prostatic origin in poorly differentiated metastatic carcinomas.
Host	Mouse
Isotype	IgG2c Kappa
Reactivity	Human
Species	Mouse

Clone No	NKX3.1
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:20-50

Product Manual	Datasheet SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
AMA55-5M	AMA55-5M	6 mL	$204		Add to Cart
AMA55-10M	AMA55-10M	100 tests - i6000	$382		Add to Cart
AXA55-50D	AXA55-50D	50 tests - Xmatrx	$213		Add to Cart
AXA55-YCD	AXA55-YCD	160 tests - Xmatrx	$523		Add to Cart
MUA55-UC	MUA55-UC	1ml Conc	$599		Add to Cart
MUA55-5UC	MUA55-5UC	0.5ml Conc	$421		Add to Cart

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