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Home / Primary Antibodies / Monoclonal Antibodies

Anti-NGF (Nerve Growth Factor) Neutralizing Antibody

SKU : BHA18200041

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BPS Bioscience

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Mfr.No.	100436-2
Background	NGF is a neurotrophic factor (NTF) that is involved in growth, proliferation and survival of neurons. Anti-NGF monoclonal antibodies are in clinical trials as a chronic pain control medicine.
Clonality	Monoclonal
Cross Reactivity	This antibody has not been tested for cross-reactivity with any other species.
Description	Anti-NGF Neutralizing Recombinant Human antibody. This antibody has not been tested for crossreactivity with other species. assay conditions: The Anti-NGF Antibody was evaluated using TrkA-SRE (Luc)- HEK293 cell line (BPS Bioscience #79798). NGF (500 pM at final concentration) was incubated with various concentrations of Anti-NGF Antibody in the assay medium (Opti-MEM) for 45 min. at room temperature and added to the cells. After 5 hour incubation at 37°C, ONE-Step Luciferase Assay System (BPS Bioscience #60690) was used to measure the luciferase activity.
Formulation	8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol
Isotype	IgG1
Species	Human
Synonyms	Anti Nerve Growth Factor

Uniprot	P01138

Format	Aqueous solution
Purification	Protein A affinity purificationfrom HEK293 supernatants.
Shipping Temperature	-80°C (dry ice)
Storage Stability	Stable for at least 12 months at -80°C.

Product Manual	Datasheet

Reference	1. Norman, B.H. et al., J. Med. Chem. 2017; 60(1): 66-88. 2. Lane, N.E., et al., N. Engl. J. Med. 2010; 363(16): 1521-1531.

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SKU	Supplier No.	Size	Your price	Quantity
BHA18200041	100436-2	100 ug	$539		Add to Cart

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