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Home / Primary Antibodies / Monoclonal Antibodies

Anti-NDFIP2 Antibody Picoband® (monoclonal, 10D6D7)

SKU : BHA21004273

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Mfr.No.	M08384, M08384-10ug, M08384-Biotin, M08384-Cy3, M08384-Dylight488, M08384-Dylight550, M08384-Dylight594, M08384-FITC, M08384-HRP, M08384-APC, M08384-PE, M08384-iFluor647, M08384-carrier-free
Alternative Names	chaperonin containing TCP1 subunit 3
Background	NEDD4 family-interacting protein 2 is a protein that in humans is encoded by the NDFIP2 gene. The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-NDFIP2 Antibody Picoband® (monoclonal, 10D6D7) catalog # M08384. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vi
Host	Mouse
Immunogen Region	E.coli-derived human NDFIP2 recombinant protein (Position: M16-L336).
Isotype	Mouse IgG2b
Molecular Weight	39 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	T-complex protein 1 subunit gamma; TCP-1-gamma; CCT-gamma; hTRiC5; CCT3; CCTG; TRIC5
Tissue Specificity	Ubiquitously expressed with highest levels in spleen, thymus and immature brain.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	Q9NV92
Gene Id	54602
Gene Name	NDFIP2
Clone No	Clone: 10D6D7
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, IHC, ICC, IF, Flow Cytometry
Description	Weste blot, 0.25-0.5 ug/ml, Human<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Cristillo, A. D., Nie, L., Macri, M. J., Bierer, B. E. Cloning and characterization of N4WBP5A, an inducible, cyclosporine-sensitive, Nedd4-binding protein in human T lymphocytes. J. Biol. Chem. 278: 34587-34597, 2003.<br /><br />2. Hirosawa, M., Nagase, T., Ishikawa, K., Kikuno, R., Nomura, N., Ohara, O. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. DNA Res. 6: 329-336, 1999. <br /><br />3. Konstas, A.-A., Shearwin-Whyatt, L. M., Fotia, A. B., Degger, B., Riccardi, D., Cook, D. I., Korbmacher, C., Kumar, S. Regulation of the epithelial sodium channel by N4WBP5A, a novel Nedd4/Nedd4-2-interacting protein. J. Biol. Chem. 277: 29406-29416, 2002.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004273-1	M08384	-	100 ug	$370		Add to Cart
BHA21004273-2	M08384-10ug	Sample	10 ug	$99		Add to Cart
BHA21004273-3	M08384-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004273-4	M08384-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004273-5	M08384-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004273-6	M08384-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004273-7	M08384-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004273-8	M08384-FITC	FITC	100 ug	$570		Add to Cart
BHA21004273-9	M08384-HRP	HRP	100 ug	$570		Add to Cart
BHA21004273-10	M08384-APC	APC	100 ug	$670		Add to Cart
BHA21004273-11	M08384-PE	PE	100 ug	$670		Add to Cart
BHA21004273-12	M08384-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004273-13	M08384-carrier-free	carrier-free	100 ug	$370		Add to Cart

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