Neutralizing recombinant human antibody recognizing the Lag-3 binding region.
assay conditions: Anti-LAG3 Neutralizing Antibody was added at various concentrations to the LAG-3/NFAT Reporter Jurkat cells (BPS Cat. #71278) co-cultured with superantigen-loaded Raji cellsand luciferase activity was measured using ONE-Step Luciferase Assay System (BPS Cat. #60690)
Formulation
8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Isotype
IgG1
Molecular Weight
Heavy chain: 51 kDa Light chain:26kDa
Species
Human
Note
Avoid freeze/thaw cycles.
Uniprot
P18627
Format
Aqueous buffer solution
Purification
Protein A affinity chromatography from HEK293 supernatants.
Shipping Temperature
-80°C (dry ice)
Storage Stability
Stable for at least 12 months at -80°C. Avoid freeze/thaw cycles. Store diluted antibody with carrier protein (BSA 0.1 - 0.5%) at 4°C, stable for 2 weeks.