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Home / Primary Antibodies / Monoclonal Antibodies

Anti-KMT5A / SETD8 / Pr-SET7 Monoclonal Antibody

SKU : BHA21008990

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Mfr.No.	M05349, M05349-30ul
Alternative Names	Kinesin-like protein KIFC1
Clonality	Monoclonal
Description	Boster Bio Anti-KMT5A / SETD8 / Pr-SET7 Monoclonal Antibody catalog # M05349. Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Function	Minus end-ed microtubule-dependent motor required for bipolar spindle formation (PubMed:15843429). May contribute to movement of early endocytic vesicles (By similarity). Regulates cilium formation and structure (By similarity). .
Host	Rabbit
Immunogen Region	A synthesized peptide derived from human KMT5A / SETD8 / Pr-SET7 Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1) . H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes.
Isotype	Rabbit IgG
Molecular Weight	72 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Synonyms	Kinesin-like protein KIFC1;Kinesin-like protein 2;Kinesin-related protein HSET;KIFC1;HSET, KNSL2;
Tissue Specificity	Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung.
Note	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Uniprot	Q9NQR1
Gene Name	KMT5A
Clone No	Clone: ADHO-11
Subcellular Location	Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Early endosome . Associated with nucleus during interphase, centrosomes in early and spindle in later mitosis. .

Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form	Liquid
Purification	Affinity-chromatography
Storage	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Applications	WB, Flow Cytometry
Description	WB 1:1000-1:5000 FC 1:100

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21008990-1	M05349	-	100 ul	$370		Add to Cart
BHA21008990-2	M05349-30ul	Sample	30 ul	$99		Add to Cart

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