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Home / Primary Antibodies / Monoclonal Antibodies

Anti-J chain

SKU : BHA15100262

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BioGenex Laboratories

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Mfr.No.	AN756-5M
Clonality	Monoclonal
Description	J chain is a small, glycopeptide of 15 kD. It is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins. J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsils and lymph nodes. B cells secrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM. J chain has been proposed to play a role in the mucosal transport of polymeric Igs by the polymeric Ig receptor. The studies show that a significant proportion of deposited mesangial immunoglobulin in IgA nephropathy is dimeric, or J chain positive. This monoclonal antibody stains J chain in cytoplasm of positve cells. B cells secrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM.
Host	Rabbit
Isotype	IgG
Reactivity	Human
Species	Rabbit

Clone No	SP105
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:50-100

Product Manual	Datasheet SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
AN756-5M	AN756-5M	6 mL	$263		Add to Cart
AN756-10M	AN756-10M	100 tests - i6000	$472		Add to Cart
AY756-50D	AY756-50D	50 tests - Xmatrx	$276		Add to Cart
AY756-YCD	AY756-YCD	160 tests - Xmatrx	$820		Add to Cart
NU756-UC	NU756-UC	1ml Conc	$616		Add to Cart
NU756-5UC	NU756-5UC	0.5ml Conc	$433		Add to Cart

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