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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Involucrin Ivl Antibody (Monoclonal, SY5)

SKU : BHA21006529

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Mfr.No.	MA1053
Alternative Names	Involucrin
Background	Involucrin is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. The gene consists of 585 amino acids, 390 of which form a central decapeptide repeat, rich in glutamine and glutamic acid. The involucrin gene, encoding a protein of the terminally differentiated keratinocyte, is polymorphic in the human. Involucrin has previously been mapped to chromosome 1q21. The epidermal protein involucrin has been remodeled in the higher primates. And the existence of two populations of East Asian involucrin alleles gives support for the existence of a Eurasian stem lineage from which Caucasians and a part of the Asian population originated.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Involucrin Ivl Antibody (Monoclonal, SY5) catalog # MA1053. Tested in IHC, ICC, WB applications. This antibody reacts with Human, Pig.
Function	Part of the insoluble coified cell envelope (CE) of stratified squamous epithelia.
Host	Mouse
Immunogen Region	Human involucrin.
Isotype	Mouse IgG1
Molecular Weight	68 kDa
Reactivity	Human, Pig
Reconstitution	Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Involucrin;Ivl;
Tissue Specificity	Keratinocytes of epidermis and other stratified squamous epithelia.
Note	Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Uniprot	P48998
Gene Id	Human(3713), Mouse(16447), Rat(60583)
Gene Name	IVL
Clone No	Clone: SY5
Sequence	Belongs to the insulin family.
Subcellular Location	Cytoplasm. Constituent of the scaffolding of the coified envelope.

Concentration	Adding 1 ml of PBS buffer will yield a concentration of 100 ug/ml.
Form	Lyophilized
Purification	Ascites
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, ICC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.4-1ug/ml, Human, pig, By Heat <br>Immunocytochemistry , 1ug/ml, Human, pig, -<br>Immunohistochemistry (Frozen Section), 0.4-1ug/ml, Human, pig, -<br>Weste blot, 1ug/ml, Human, pig<br>

Reference	1. Eckert, R. L.; Green, H. : Structure and evolution of the human involucrin gene. Cell 46: 583-589, 1986.<br /><br />2. Djian, P.; Delhomme, B.; Green, H. : Origin of the polymorphism of the involucrin gene in Asians. Am. J. Hum. Genet. 56: 1367-1372, 1995.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006529-1	MA1053	-	100 ug	$370		Add to Cart

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