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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Integrin linked ILK Antibody Picoband® (monoclonal, 3C7E1)

SKU : BHA21004297

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Mfr.No.	M02932-2, M02932-2-10ug, M02932-2-Biotin, M02932-2-Cy3, M02932-2-Dylight488, M02932-2-Dylight550, M02932-2-Dylight594, M02932-2-FITC, M02932-2-HRP, M02932-2-APC, M02932-2-PE, M02932-2-iFluor647, M02932-2-carrier-free
Alternative Names	high mobility group box 3
Background	ILK, also known as Integrin-linked kinase, is a serine-threonine protein kinase. Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK) interacts with the cytoplasmic domain of beta-1 integrin. This gene was initially described to encode a serine/ threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alteatively spliced transcript variants encoding the same protein have been found for this gene. Recent results showed that ILK contains 5 ankyrin-like repeats, and that the C-terminal kinase domain is actually a pseudo-kinase with adaptor function.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Integrin linked ILK Antibody Picoband® (monoclonal, 3C7E1) catalog # M02932-2. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Multifunctional protein with various roles in different cellular compartments,May act in a redox sensitive manner.Associates with chromatin and binds DNA with a preference to non- canonical DNA structures such as single-stranded DNA. Can bent DNA and enha
Host	Mouse
Immunogen Region	E.coli-derived human Integrin linked ILK recombinant protein (Position: M1-K452).
Isotype	Mouse IgG2b
Molecular Weight	51 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	"chromosomal protein, Nonhistone, HMG4 antibody\|High mobility group (nonhistone chromosomal) protein 4 antibody\|High mobility group box 3 antibody\|High mobility group protein 2a antibody\|High mobility group protein 4 antibody\|High mobility group protein B3 antibody\|High mobility group protein HMG4 antibody\|HMG 4 antibody\|HMG-2a antibody\|HMG-4 antibody\|HMG2A antibody\|HMGB 3 antibody\|HMGB3 antibody\| HMGB3_HUMAN antibody\|MGC90319 antibody\|Non histone chromosomal protein antibody\|Nonhistone chromosomal protein HMG4 antibody"
Tissue Specificity	Expressed predominantly in placenta.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	Q13418
Gene Id	3611
Gene Name	ILK
Clone No	Clone: 3C7E1
Subcellular Location	Nucleus . Chromosome . Cytoplasm .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, IHC
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human, Mouse<br>

Reference	1."Entrez Gene: ILK integrin-linked kinase".<br /><br />2.Fielding AB, Dobreva I, McDonald PC, Foster LJ, Dedhar S (Feb 2008). "Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization". The Joual of Cell Biology 180 (4): 6819.<br /><br />3.Melchior, C., Kreis, S., Janji, B., Kieffer, N. Promoter characterization and genomic organization of the gene encoding integrin-linked kinase 1. Biochim. Biophys. Acta 1575: 117-122, 2002.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004297-1	M02932-2	-	100 ug	$370		Add to Cart
BHA21004297-2	M02932-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21004297-3	M02932-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004297-4	M02932-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004297-5	M02932-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004297-6	M02932-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004297-7	M02932-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004297-8	M02932-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21004297-9	M02932-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21004297-10	M02932-2-APC	APC	100 ug	$670		Add to Cart
BHA21004297-11	M02932-2-PE	PE	100 ug	$670		Add to Cart
BHA21004297-12	M02932-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004297-13	M02932-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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