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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Integrin beta 5/ITGB5 Antibody Picoband® (monoclonal, 9E2)

SKU : BHA21003236

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Mfr.No.	M04201, M04201-10ug, M04201-Biotin, M04201-Cy3, M04201-Dylight488, M04201-Dylight550, M04201-Dylight594, M04201-FITC, M04201-HRP, M04201-APC, M04201-PE, M04201-iFluor647, M04201-carrier-free
Alternative Names	heat shock 105kDa/110kDa protein 1
Background	This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Integrin beta 5/ITGB5 Antibody Picoband® (monoclonal, 9E2) catalog # M04201. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate protein release. Prevents the aggregation of denatured proteins in cells under severe stres
Host	Mouse
Immunogen Region	E.coli-derived human Integrin beta 5/ITGB5 recombinant protein (Position: S32-D689).
Isotype	Mouse IgG1
Molecular Weight	100 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Heat shock protein 105 kDa; Antigen NY-CO-25; Heat shock 110 kDa protein; HSPH1; HSP105; HSP110; KIAA0201
Tissue Specificity	Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Uniprot	P18084
Gene Id	3693
Gene Name	ITGB5
Clone No	Clone: 9E2
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, Flow Cytometry
Description	Weste blot, 0.25-0.5ug/ml, Human<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Busk, M., Pytela, R., Sheppard, D. Characterization of the integrin alpha-v-beta-6 as a fibronectin-binding protein. J. Biol. Chem. 267: 5790-5796, 1992.<br /><br />2. McLean, J. W., Vestal, D. J., Cheresh, D. A., Bodary, S. C. cDNA sequence of the human integrin beta 5 subunit. J. Biol. Chem. 265: 17126-17131, 1990.<br /><br />3. Reynolds, L. E., Wyder, L., Lively, J. C., Tavea, D., Robinson, S. D., Huang, X., Sheppard, D., Hynes, R. O., Hodivala-Dilke, K. M. Enhanced pathological angiogenesis in mice lacking beta-3 integrin or beta-3 and beta-5 integrins. Nature Med. 8: 27-34, 2002.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003236-1	M04201	-	100 ug	$370		Add to Cart
BHA21003236-2	M04201-10ug	Sample	10 ug	$99		Add to Cart
BHA21003236-3	M04201-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003236-4	M04201-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003236-5	M04201-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003236-6	M04201-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003236-7	M04201-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003236-8	M04201-FITC	FITC	100 ug	$570		Add to Cart
BHA21003236-9	M04201-HRP	HRP	100 ug	$570		Add to Cart
BHA21003236-10	M04201-APC	APC	100 ug	$670		Add to Cart
BHA21003236-11	M04201-PE	PE	100 ug	$670		Add to Cart
BHA21003236-12	M04201-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003236-13	M04201-carrier-free	carrier-free	100 ug	$370		Add to Cart

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