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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Human VE-Cadherin CDH5 DyLight® 488 conjugated Antibody(monoclonal, 3D4)

SKU : BHA21002505

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Mfr.No.	M02632-Dyl488
Alternative Names	cadherin 5
Background	CDH5 (Cadherin 5), also known as VE-cadherin, is a type of cadherin. It is encoded by the human gene CDH5. This gene is mapped to 16q22.1 using somatic cell hybrid panels. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Therefore it was concluded that VE-cadherin serves the purpose of maintaining newly formed vessels.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Human VE-Cadherin CDH5 DyLight® 488 conjugated Antibody (monoclonal, 3D4) catalog # M02632-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.
Function	Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (PubMed:21269602). Th
Host	Mouse
Immunogen Region	E. coli-derived human VE Cadherin recombinant protein (Position: D48-R272).
Isotype	Mouse IgG1
Molecular Weight	39 kDa
Reactivity	Human
Specificity	No cross reactivity with other proteins.
Synonyms	Cadherin-5; 7B4 antigen; Vascular endothelial cadherin; VE-cadherin; CD144; CDH5
Note	Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN7.

Uniprot	P33151
Gene Id	1003
Gene Name	CDH5
Clone No	Clone: 3D4
Subcellular Location	Plasma membrane

Conjugates	DyLight 488

Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form	Liquid
Storage	At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications	Flow Cytometry
Description	Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, human<br>

Reference	1. Huber, P., Dalmon, J., Engiles, J., Breviario, F., Gory, S., Siracusa, L. D., Buchberg, A. M., Dejana, E. Genomic structure and chromosomal mapping of the mouse VE-cadherin gene (Cdh5). Genomics 32: 21-28, 1996.<br /><br />2. Kremmidiotis, G., Baker, E., Crawford, J., Eyre, H. J., Nahmias, J., Callen, D. F. Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity. Genomics 49: 467-471, 1998.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002505-1	M02632-Dyl488	-	100 ug	$515		Add to Cart

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