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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Hsp90 beta/HSP90AB1 Antibody Picoband® (monoclonal, 7B7F5)

SKU : BHA21004828

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Mfr.No.	M01692-4, M01692-4-10ug, M01692-4-Biotin, M01692-4-Cy3, M01692-4-Dylight488, M01692-4-Dylight550, M01692-4-Dylight594, M01692-4-FITC, M01692-4-HRP, M01692-4-APC, M01692-4-PE, M01692-4-iFluor647, M01692-4-carrier-free
Alternative Names	melanoma cell adhesion molecule
Background	Heat shock protein HSP 90-beta, also called HSP90beta, is a protein that in humans is encoded by the HSP90AB1 gene. It is mapped to chromosome 6p21.1. This gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. And this gene is thought to play a role in gastric apoptosis and inflammation. Alteative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Hsp90 beta/HSP90AB1 Antibody Picoband® (monoclonal, 7B7F5) catalog # M01692-4. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous t
Host	Mouse
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human Hsp90 beta, identical to the related mouse and rat sequences.
Isotype	IgG2b
Molecular Weight	90 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	A32 antigen antibody; CD 146 antibody; CD146 antibody; CD146 antigen antibody; Cell surface glycoprotein MUC18 antibody; Cell surface glycoprotein P1H12 antibody; Gicerin antibody; MCAM antibody; Melanoma adhesion molecule antibody; Melanoma associated antigen A32 antibody; Melanoma associated antigen MUC18 antibody; Melanoma associated glycoprotein MUC18 antibody; Melanoma cell adhesion molecule antibody; Melanoma-associated antigen A32 antibody; Melanoma-associated antigen MUC18 antibody; MelCAM antibody; MUC 18 antibody; MUC18 antibody; MUC18_HUMAN antibody; S endo 1 antibody; S endo 1 endothelial associated antigen antibody; S-endo 1 endothelial-associated antigen antibody; Sendo 1 endothelial associated antigen antibody; Sendo1 antibody
Tissue Specificity	Detected in endothelial cells in vascular tissue throughout the body. May appear at the surface of neural crest cells during their embryonic migration. Appears to be limited to vascular smooth muscle in normal adult tissues. Associated with tumor progression and the development of metastasis in human malignant melanoma. Expressed most strongly on metastatic lesions and advanced primary tumors and is only rarely detected in benign melanocytic nevi and thin primary melanomas with a low probability of metastasis.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P08238
Gene Id	3326
Gene Name	HSP90AB1
Clone No	Clone: 7B7F5
Subcellular Location	Membrane. Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, ICC, IF, Flow Cytometry
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human

Reference	1. "Entrez Gene: HSP90AB1 Heat shock protein 90kDa alpha (cytosolic), class B member 1". 2. Chen B, Piel WH, Gui L, Bruford E, Monteiro A (Dec 2005). "The HSP90 family of genes in the human genome: insights into their divergence and evolution". Genomics 86 (6): 62737. 3. Rebbe NF, Hickman WS, Ley TJ, Stafford DW, Hickman S (Sep 1989). "Nucleotide sequence and regulation of a human 90-kDa heat shock protein gene". The Joual of Biological Chemistry 264 (25): 1500611.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004828-1	M01692-4	-	100 ug	$370		Add to Cart
BHA21004828-2	M01692-4-10ug	Sample	10 ug	$99		Add to Cart
BHA21004828-3	M01692-4-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004828-4	M01692-4-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004828-5	M01692-4-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004828-6	M01692-4-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004828-7	M01692-4-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004828-8	M01692-4-FITC	FITC	100 ug	$570		Add to Cart
BHA21004828-9	M01692-4-HRP	HRP	100 ug	$570		Add to Cart
BHA21004828-10	M01692-4-APC	APC	100 ug	$670		Add to Cart
BHA21004828-11	M01692-4-PE	PE	100 ug	$670		Add to Cart
BHA21004828-12	M01692-4-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004828-13	M01692-4-carrier-free	carrier-free	100 ug	$370		Add to Cart

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