JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / Monoclonal Antibodies

Anti-GSDMD Antibody Picoband® (monoclonal, 6D11)

SKU : BHA21003451

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

Boster

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	M02842, M02842-10ug, M02842-Biotin, M02842-Cy3, M02842-Dylight488, M02842-Dylight550, M02842-Dylight594, M02842-FITC, M02842-HRP, M02842-APC, M02842-PE, M02842-iFluor647, M02842-carrier-free
Alternative Names	high mobility group box 3
Background	Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alteatively spliced transcript variants have been described.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-GSDMD Antibody Picoband® (monoclonal, 6D11) catalog # M02842. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Multifunctional protein with various roles in different cellular compartments,May act in a redox sensitive manner.Associates with chromatin and binds DNA with a preference to non- canonical DNA structures such as single-stranded DNA. Can bent DNA and enha
Host	Mouse
Immunogen Region	E.coli-derived human GSDMD recombinant protein (Position: M1-H484).
Isotype	Mouse IgG2b
Molecular Weight	53 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	"chromosomal protein, Nonhistone, HMG4 antibody\|High mobility group (nonhistone chromosomal) protein 4 antibody\|High mobility group box 3 antibody\|High mobility group protein 2a antibody\|High mobility group protein 4 antibody\|High mobility group protein B3 antibody\|High mobility group protein HMG4 antibody\|HMG 4 antibody\|HMG-2a antibody\|HMG-4 antibody\|HMG2A antibody\|HMGB 3 antibody\|HMGB3 antibody\| HMGB3_HUMAN antibody\|MGC90319 antibody\|Non histone chromosomal protein antibody\|Nonhistone chromosomal protein HMG4 antibody"
Tissue Specificity	Expressed predominantly in placenta.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P57764
Gene Id	79792
Gene Name	GSDMD
Clone No	Clone: 6D11
Subcellular Location	Nucleus . Chromosome . Cytoplasm .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, IHC, ICC, IF, Flow Cytometry
Description	Weste blot, 0.25-0.5 ug/ml, Human<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Ruhl, S., Shkarina, K., Demarco, B., Heilig, R., Santos, J. C., Broz, P. ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation. Science 362: 956-960, 2018.<br /><br />2. Shi, J., Zhao, Y., Wang, K., Shi, X., Wang, Y., Huang, H., Zhuang, Y., Cai, T., Wang, F., Shao, F. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. Nature 526: 660-665, 2015. <br /><br />3. Zhu, Q., Zheng, M., Balakrishnan, A., Karki, R., Kanneganti, T.-D. Gasdermin D promotes AIM2 inflammasome activation and is required for host protection against Francisella novicida. J. Immun. 201: 3662-3668, 2018.

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003451-1	M02842	-	100 ug	$370		Add to Cart
BHA21003451-2	M02842-10ug	Sample	10 ug	$99		Add to Cart
BHA21003451-3	M02842-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003451-4	M02842-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003451-5	M02842-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003451-6	M02842-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003451-7	M02842-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003451-8	M02842-FITC	FITC	100 ug	$570		Add to Cart
BHA21003451-9	M02842-HRP	HRP	100 ug	$570		Add to Cart
BHA21003451-10	M02842-APC	APC	100 ug	$670		Add to Cart
BHA21003451-11	M02842-PE	PE	100 ug	$670		Add to Cart
BHA21003451-12	M02842-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003451-13	M02842-carrier-free	carrier-free	100 ug	$370		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.