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Home / Primary Antibodies / Monoclonal Antibodies

Anti-FcGR3A (CD16A) IgG Antibody, Biotin-Labeled

SKU : BHA18200073

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BPS Bioscience

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Mfr.No.	101225-2
Clonality	Monoclonal
Cross Reactivity	This antibody recognizes human FcGR3A/CD16A. It does not recognize human FcGR3B (CD16B). It has not been tested with other species
Description	This anti-FcGR3A (CD16A) antibody is a purified, biotinylated, recombinant human monoclonal antibody which recognizes the human FcGR3A/CD16A protein. Fc Gamma Receptor IIIa (FcGRIIIA; FcgammaRIIIA), also known as CD16a, is a low/intermediate affinity receptor for polyvalent immune-complexed IgG. It is involved in phagocytosis, antibody-dependent cytotoxicity, and clearance of immune complexes. FcGR3A/CD16A plays a role in the activation of natural killer (NK) cells. Clinically, it serves as a marker of certain immune cells such as neutrophils. CD16 expression has been observed at the surface of T cells in patients with chronic viral infections (such as COVID-19). It is considered a potential therapeutic target to potentiate the efficacy of therapeutic antibodies used to treat solid tumors, or as direct target in hematopoietic cancers.This antibody has been tested for specific binding to purified human FcGR3A/CD16A (BPS Bioscience #79013) in an ELISA binding assay with colorimetric detection. It does not cross-react with purified human FcGR2B/CD16B.
Formulation	8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Isotype	IgG1
Molecular Weight	~150 kDa
Species	Human
Synonyms	Low affinity immunoglobulin gamma Fc region receptor III-A, CD16a antigen, Fc-gamma RIII-alpha, FcR-10, IgG Fc receptor III-2, CD_antigen: CD16a
Note	Avoid freeze/thaw cycles.

Format	Aqueous buffer solution
Purification	Protein A affinity chromatography from HEK293 supernatants.
Purity	>=90%
Shipping Temperature	-80°C (dry ice)
Storage Stability	At least 12 months at -80°C.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA18200073	101225-2	100 ug	$412.50		Add to Cart

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