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Home / Primary Antibodies / Monoclonal Antibodies

Anti-FACL4/ACSL4 Antibody Picoband® (monoclonal, 4I7)

SKU : BHA21003838

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Mfr.No.	M04372, M04372-10ug, M04372-Biotin, M04372-Cy3, M04372-Dylight488, M04372-Dylight550, M04372-Dylight594, M04372-FITC, M04372-HRP, M04372-APC, M04372-PE, M04372-iFluor647, M04372-carrier-free
Alternative Names	heat shock 105kDa/110kDa protein 1
Background	Long-chain-fatty-acidCoA ligase 4 is an enzyme that in humans is encoded by the ACSL4 gene. It is mapped to Xq23. The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the cognitive disability or Alport syndrome. Alteative splicing of this gene generates multiple transcript variants.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-FACL4/ACSL4 Antibody Picoband® (monoclonal, 4I7) catalog # M04372. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate protein release. Prevents the aggregation of denatured proteins in cells under severe stres
Host	Mouse
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human FACL4/ACSL4.
Isotype	Mouse IgG1
Molecular Weight	79 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Heat shock protein 105 kDa; Antigen NY-CO-25; Heat shock 110 kDa protein; HSPH1; HSP105; HSP110; KIAA0201
Tissue Specificity	Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	O60488
Gene Id	2182
Gene Name	ACSL4
Clone No	Clone: 4I7
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, IHC, ICC, IF, Flow Cytometry
Description	Weste blot, 0.25-0.5 ug/ml, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human

Reference	1. Piccini M, Vitelli F, Bruttini M, Pober BR, Jonsson JJ, Villanova M, Zollo M, Borsani G, Ballabio A, Renieri A (Apr 1998). "FACL4, a new gene encoding long-chain acyl-CoA synthetase 4, is deleted in a family with Alport syndrome, elliptocytosis, and mental retardation". Genomics. 47 (3): 3508. 2. Verot L, Alloisio N, Morle L, Bozon M, Touraine R, Plauchu H, Edery P (Sep 2003). "Localization of a non-syndromic X-linked mental retardation gene (MRX80) to Xq22-q24". Am J Med Genet A. 122A (1): 3741. 3. Zong NC, Li H, Li H, Lam MP, Jimenez RC, Kim CS, Deng N, Kim AK, Choi JH, Zelaya I, Liem D, Meyer D, Odeberg J, Fang C, Lu HJ, Xu T, Weiss J, Duan H, Uhlen M, Yates JR, Apweiler R, Ge J, Hermjakob H, Ping P (Oct 2013). "Integration of cardiac proteome biology and medicine by a specialized knowledgebase". Circulation Research. 113 (9): 104353.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003838-1	M04372	-	100 ug	$370		Add to Cart
BHA21003838-2	M04372-10ug	Sample	10 ug	$99		Add to Cart
BHA21003838-3	M04372-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003838-4	M04372-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003838-5	M04372-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003838-6	M04372-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003838-7	M04372-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003838-8	M04372-FITC	FITC	100 ug	$570		Add to Cart
BHA21003838-9	M04372-HRP	HRP	100 ug	$570		Add to Cart
BHA21003838-10	M04372-APC	APC	100 ug	$670		Add to Cart
BHA21003838-11	M04372-PE	PE	100 ug	$670		Add to Cart
BHA21003838-12	M04372-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003838-13	M04372-carrier-free	carrier-free	100 ug	$370		Add to Cart

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