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Home / Primary Antibodies / Monoclonal Antibodies

Anti-EPRS1/PARS Antibody Picoband® (monoclonal, 12B5B3)

SKU : BHA21003832

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Mfr.No.	M02967, M02967-10ug, M02967-Biotin, M02967-Cy3, M02967-Dylight488, M02967-Dylight550, M02967-Dylight594, M02967-FITC, M02967-HRP, M02967-APC, M02967-PE, M02967-iFluor647, M02967-carrier-free
Alternative Names	high mobility group box 3
Background	Bifunctional aminoacyl-tRNA synthetase is an enzyme that in humans is encoded by the EPRS gene. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species. Alteative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-EPRS1/PARS Antibody Picoband® (monoclonal, 12B5B3) catalog # M02967. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Multifunctional protein with various roles in different cellular compartments,May act in a redox sensitive manner.Associates with chromatin and binds DNA with a preference to non- canonical DNA structures such as single-stranded DNA. Can bent DNA and enha
Host	Mouse
Immunogen Region	E.coli-derived human EPRS1/PARS recombinant protein (Position: R1298-Y1512).
Isotype	Mouse IgG2b
Molecular Weight	170-180 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	"chromosomal protein, Nonhistone, HMG4 antibody\|High mobility group (nonhistone chromosomal) protein 4 antibody\|High mobility group box 3 antibody\|High mobility group protein 2a antibody\|High mobility group protein 4 antibody\|High mobility group protein B3 antibody\|High mobility group protein HMG4 antibody\|HMG 4 antibody\|HMG-2a antibody\|HMG-4 antibody\|HMG2A antibody\|HMGB 3 antibody\|HMGB3 antibody\| HMGB3_HUMAN antibody\|MGC90319 antibody\|Non histone chromosomal protein antibody\|Nonhistone chromosomal protein HMG4 antibody"
Tissue Specificity	Expressed predominantly in placenta.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P07814
Gene Id	2058
Gene Name	EPRS1
Clone No	Clone: 12B5B3
Subcellular Location	Nucleus . Chromosome . Cytoplasm .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, IHC, ICC, IF, Flow Cytometry
Description	Weste blot, 0.25-0.5 ug/ml, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human

Reference	1. Arif, A., Jia, J., Mukhopadhyay, R., Willard, B., Kinter, M., Fox, P. L. Two-site phosphorylation of EPRS coordinates multinodal regulation of noncanonical translational control activity. Molec. Cell 35: 164-180, 2009. 2. Arif, A., Terenzi, F., Potdar, A. A., Jia, J., Sacks, J., China, A., Halawani, D., Vasu, K., Li, X., Brown, J. M., Chen, J., Kozma, S. C., Thomas, G., Fox, P. L. EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice. Nature 542: 357-361, 2017. 3. Cerini, C., Kerjan, P., Astier, M., Gratecos, D., Mirande, M., Semeriva, M. A component of the multisynthetase complex is a multifunctional aminoacyl-tRNA synthetase. EMBO J. 10: 4267-4277, 1991.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003832-1	M02967	-	100 ug	$370		Add to Cart
BHA21003832-2	M02967-10ug	Sample	10 ug	$99		Add to Cart
BHA21003832-3	M02967-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003832-4	M02967-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003832-5	M02967-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003832-6	M02967-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003832-7	M02967-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003832-8	M02967-FITC	FITC	100 ug	$570		Add to Cart
BHA21003832-9	M02967-HRP	HRP	100 ug	$570		Add to Cart
BHA21003832-10	M02967-APC	APC	100 ug	$670		Add to Cart
BHA21003832-11	M02967-PE	PE	100 ug	$670		Add to Cart
BHA21003832-12	M02967-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003832-13	M02967-carrier-free	carrier-free	100 ug	$370		Add to Cart

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