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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Emerin EMD Antibody Picoband® (monoclonal, 5A10)

SKU : BHA21001763

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Mfr.No.	M00714, M00714-10ug, M00714-Biotin, M00714-Cy3, M00714-Dylight488, M00714-Dylight550, M00714-Dylight594, M00714-FITC, M00714-HRP, M00714-APC, M00714-PE, M00714-iFluor647, M00714-carrier-free
Alternative Names	emerin
Background	APOBEC3G (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G) is a human enzyme encoded by the APOBEC3G gene. This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. The protein encoded by this gene has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Emerin EMD Antibody Picoband® (monoclonal, 5A10) catalog # M00714. Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucle
Host	Mouse
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human Emerin, different from the related mouse sequence by eight amino acids, and from the related rat sequence by nine amino acids.
Isotype	Mouse IgG1
Molecular Weight	34 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Emerin; EMD; EDMD; STA
Tissue Specificity	Skeletal muscle, heart, colon, testis, ovary and pancreas.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P50402
Gene Id	2010
Gene Name	EMD
Clone No	Clone: 5A10
Subcellular Location	Nucleus inner membrane

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml<br> Immunohistochemistry (Frozen Section), 0.5-1ug/ml<br> Immunocytochemistry, 0.5-1ug/ml<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells<br>

Reference	1. "Entrez Gene: EMD emerin (EmeryDreifuss muscular dystrophy)". <br /><br />2. Lammerding, J; Hsiao, J; Schulze, PC; Kozlov, S; Stewart, CL; Lee, RT (29 August 2005). "Abnormal nuclear shape and impaired mechanotransduction in emerin-deficient cells.". The Joual of Cell Biology. 170 (5): 78191. <br /><br />3. Nagano A, Koga R, Ogawa M, Kurano Y, Kawada J, Okada R, Hayashi YK, Tsukahara T, Arahata K (Mar 1996). "Emerin deficiency at the nuclear membrane in patients with EmeryDreifuss muscular dystrophy". Nature Genetics. 12 (3): 2549.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001763-1	M00714	100 ug	-	$370		Add to Cart
BHA21001763-2	M00714-10ug	10 ug	Sample	$99		Add to Cart
BHA21001763-3	M00714-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001763-4	M00714-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001763-5	M00714-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001763-6	M00714-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001763-7	M00714-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001763-8	M00714-FITC	100 ug	FITC	$570		Add to Cart
BHA21001763-9	M00714-HRP	100 ug	HRP	$570		Add to Cart
BHA21001763-10	M00714-APC	100 ug	APC	$670		Add to Cart
BHA21001763-11	M00714-PE	100 ug	PE	$670		Add to Cart
BHA21001763-12	M00714-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001763-13	M00714-carrier-free	100 ug	carrier-free	$370		Add to Cart

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