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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CPSF6 Antibody Picoband® (monoclonal, 3F11E1)

SKU : BHA21004426

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Mfr.No.	M04551, M04551-10ug, M04551-Biotin, M04551-Cy3, M04551-Dylight488, M04551-Dylight550, M04551-Dylight594, M04551-FITC, M04551-HRP, M04551-APC, M04551-PE, M04551-iFluor647, M04551-carrier-free
Alternative Names	coatomer protein complex subunit epsilon
Background	Cleavage and polyadenylation specificity factor subunit 6 is a protein that in humans is encoded by the CPSF6 gene. The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-CPSF6 Antibody Picoband® (monoclonal, 3F11E1) catalog # M04551. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The
Host	Mouse
Immunogen Region	E.coli-derived human CPSF6 recombinant protein (Position: R50-Q176).
Isotype	Mouse IgG1
Molecular Weight	68 kDa
Reactivity	Human, Mouse, Rat, Monkey
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Coatomer subunit epsilon; Epsilon-coat protein; Epsilon-COP; COPE
Tissue Specificity	Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	Q16630
Gene Id	11052
Gene Name	CPSF6
Clone No	Clone: 3F11E1
Subcellular Location	Golgi apparatus membrane. Peripheral membrane protein. Cytoplasmic side. Cytoplasm. COPI-coated vesicle membrane.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, IHC, ICC, IF, Flow Cytometry
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat, Monkey<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Rasaiyaah, J., Tan, C. P., Fletcher, A. J., Price, A. J., Blondeau, C., Hilditch, L., Jacques, D. A., Selwood, D. L., James, L. C., Noursadeghi, M., Towers, G. J. HIV-1 evades innate immune recognition through specific cofactor recruitment. Nature 503: 402-405, 2013.<br /><br />2. Ruegsegger, U., Blank, D., Keller, W. Human pre-mRNA cleavage factor I-m is related to spliceosomal SR proteins and can be reconstituted in vitro from recombinant subunits. Molec. Cell 1: 243-253, 1998.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004426-1	M04551	-	100 ug	$370		Add to Cart
BHA21004426-2	M04551-10ug	Sample	10 ug	$99		Add to Cart
BHA21004426-3	M04551-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004426-4	M04551-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004426-5	M04551-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004426-6	M04551-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004426-7	M04551-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004426-8	M04551-FITC	FITC	100 ug	$570		Add to Cart
BHA21004426-9	M04551-HRP	HRP	100 ug	$570		Add to Cart
BHA21004426-10	M04551-APC	APC	100 ug	$670		Add to Cart
BHA21004426-11	M04551-PE	PE	100 ug	$670		Add to Cart
BHA21004426-12	M04551-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004426-13	M04551-carrier-free	carrier-free	100 ug	$370		Add to Cart

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