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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Collagen, Type III Col3a1 Antibody (Monoclonal, FH-7A)

SKU : BHA21006513

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Mfr.No.	MA1029
Alternative Names	Collagen alpha-1(III) chain
Background	Collagen type III, also known as COL3A1, is assigned to chromosome 2. Ultrastructural analysis of tissues from mutant mice revealed that type III collagen is essential for normal collagen I fibrillogenesis in the cardiovascular system and other organs. Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular development.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio <a href="https://www.bosterbio.com/anti-collagen-i-antibody-pa2140-1-boster.html" style="color:#EA8D28">Anti-Collagen</a>, Type III Col3a1 Antibody (Monoclonal, FH-7A) catalog # MA1029. Tested in IHC, WB applications. This antibody reacts with Human, Rat.
Function	Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the
Host	Mouse
Immunogen Region	Human collagen type III.
Isotype	Mouse IgG1
Molecular Weight	49 kDa
Reactivity	Human, Rat
Reconstitution	Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Collagen alpha-1 (III) chain;Col3a1;
Tissue Specificity	Expressed on the plasma membrane of hepatocytes and in the narrow apical portions of supporting cells in the vomeronasal sensory epithelium. Detected in the type III alveolar cells of the lung, in the proliferative crypt epithelium of the small intestine and in the older intragemmal cells of the tongue. .
Note	Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Uniprot	P13941
Gene Id	Human(1281), Mouse(12825), Rat(84032)
Gene Name	COL3A1
Clone No	Clone: FH-7A
Sequence	Belongs to the fibrillar collagen family.
Subcellular Location	Secreted, extracellular space, extracellular matrix .

Concentration	Adding 1 ml of PBS buffer will yield a concentration of 100 ug/ml.
Form	Lyophilized
Purification	Ascites
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Frozen Section), 0.5-1ug/ml, Human, rat, -<br>Weste blot, 0.25-0.5ug/ml, Human, rat<br>

Reference	1. Cutting, G. R.; McGinniss, M. J.; Kasch, I. M.; Tsipouras, P.; Antonarakis, S. E. : Physical mapping by PFGE localizes the COL3A1 and COL5A2 genes to a 35 kb region on chromosome 2. (Abstract) Clin. Res. 38: 266A, 1990. <br /><br />2. Emanuel, B. S.; Cannizzaro, L. A.; Seyer, J. M.; Myers, J. C. : Human alpha-1(III) and alpha-2(V) procollagen genes are located on the long arm of chromosome 2. Proc. Nat. Acad. Sci. 82: 3385-3389, 1985. <br /><br />3. Liu, X.; Wu, H.; Bye, M.; Krane, S.; Jaenisch, R. : Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular development. Proc. Nat. Acad. Sci. 94: 1852-1856, 1997.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006513-1	MA1029	-	100 ug	$370		Add to Cart

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