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Home / Primary Antibodies / Monoclonal Antibodies

Anti-ch TOG/CKAP5 Antibody Picoband® (monoclonal, 3C13)

SKU : BHA21003091

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Mfr.No.	M05324, M05324-10ug, M05324-Biotin, M05324-Cy3, M05324-Dylight488, M05324-Dylight550, M05324-Dylight594, M05324-FITC, M05324-HRP, M05324-APC, M05324-PE, M05324-iFluor647, M05324-carrier-free
Alternative Names	aldo-keto reductase family 1 member D1
Background	Cytoskeleton-associated protein 5 is a microtubule-associated protein that in humans is encoded by the CKAP5 gene. It is mapped to 11p11.2. This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for ional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interact eatively spliced transcript variants encoding different isoforms have been identified.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-ch TOG/CKAP5 Antibody Picoband® (monoclonal, 3C13) catalog # M05324. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta4-3-one structure to yield an A/B cis-ring junction. This cis-configuration is crucial for bile acid biosynthes
Host	Mouse
Immunogen Region	E.coli-derived human ch TOG/CKAP5 recombinant protein (Position: M1-L221).
Isotype	Mouse IgG2b
Molecular Weight	225 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	3-oxo-5-beta-steroid 4-dehydrogenase; Aldo-keto reductase family 1 member D1; Delta (4)-3-ketosteroid 5-beta-reductase; Delta (4)-3-oxosteroid 5-beta-reductase; AKR1D1; SRD5B1
Tissue Specificity	Highly expressed in liver. Expressed in testis and weakly in colon.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Uniprot	Q14008
Gene Id	9793
Gene Name	CKAP5
Clone No	Clone: 3C13
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, ICC, IF, Flow Cytometry
Description	Weste blot, 0.25-0.5ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, Rat<br> Immunocytochemistry/Immunofluorescence, 5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br>

Reference	1."Entrez Gene: CKAP5 cytoskeleton associated protein 5".<br /><br />2.Charrasse S, Mazel M, Taviaux S, Berta P, Chow T, Larroque C (Feb 1996). "Characterization of the cDNA and patte of expression of a new gene over-expressed in human hepatomas and colonic tumors". Eur. J. Biochem. 234 (2): 40613.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003091-1	M05324	-	100 ug	$370		Add to Cart
BHA21003091-2	M05324-10ug	Sample	10 ug	$99		Add to Cart
BHA21003091-3	M05324-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003091-4	M05324-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003091-5	M05324-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003091-6	M05324-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003091-7	M05324-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003091-8	M05324-FITC	FITC	100 ug	$570		Add to Cart
BHA21003091-9	M05324-HRP	HRP	100 ug	$570		Add to Cart
BHA21003091-10	M05324-APC	APC	100 ug	$670		Add to Cart
BHA21003091-11	M05324-PE	PE	100 ug	$670		Add to Cart
BHA21003091-12	M05324-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003091-13	M05324-carrier-free	carrier-free	100 ug	$370		Add to Cart

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