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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CDKN2A/p14ARF Rabbit Monoclonal Antibody

SKU : BHA21009425

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Mfr.No.	M00016-2, M00016-2-30ul
Alternative Names	Signal transducer and activator of transcription 3
Clonality	Monoclonal
Description	Boster Bio Anti-CDKN2A/p14ARF Rabbit Monoclonal Antibody catalog # M00016-2. Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.
Function	Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive el
Host	Rabbit
Immunogen Region	A synthesized peptide derived from human CDKN2A/p14ARF
Isotype	IgG
Molecular Weight	36 kDa
Reactivity	Human
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Synonyms	Signal transducer and activator of transcription 3;Acute-phase response factor;STAT3;APRF;
Tissue Specificity	Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Note	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Uniprot	P42771/Q8N726
Gene Name	CDKN2A
Clone No	Clone: 19C26
Subcellular Location	Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm. Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4. Constitutive nuclear presence is independent of tyrosine phosphorylation. Predominantly present in the cytoplasm without stimuli. Upon leukemia inhibitory factor (LIF) stimulation, accumulates in the nucleus. The complex composed of BART and ARL2 plays an important role in the nuclear translocation and retention of STAT3. Identified in a complex with LYN and PAG1.

Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form	Liquid
Purification	Affinity-chromatography
Storage	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Applications	WB, ICC, IF, IP, Flow Cytometry
Description	WB 1:500-1:1000<br>ICC/IF 1:50-1:200<br>IP 1:50<br>FC 1:80

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21009425-1	M00016-2	-	100 ul	$370		Add to Cart
BHA21009425-2	M00016-2-30ul	Sample	30 ul	$99		Add to Cart

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