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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Cdk2 Antibody Picoband® (monoclonal, 5B12D1)

SKU : BHA21004090

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Mfr.No.	M00166-3, M00166-3-10ug, M00166-3-Biotin, M00166-3-Cy3, M00166-3-Dylight488, M00166-3-Dylight550, M00166-3-Dylight594, M00166-3-FITC, M00166-3-HRP, M00166-3-APC, M00166-3-PE, M00166-3-iFluor647, M00166-3-carrier-free
Alternative Names	solute carrier family 2 (facilitated glucose transporter), member 1
Background	CDK2, Cyclin-Dependent Kinase2, is also known as P33. The CDK2 protein was highly homologous to p34(CDC2) kinase and more significantly homologous to Xenopus Eg1 kinase, suggesting that CDK2 is the human homolog of Eg1. The CDK2 gene is mapped to 12q13, the same region to which the CDK4 gene maps. Human cyclin A binds independently to 2 kinases, p34(cdc2) or p33. In adenovirus-transformed cells, the viral E1A oncoprotein seems to associate with p33/cyclin A but not with p34(cdc2)/cyclin A. The gene for p33 shares 65% sequence identity with p34(cdc2). P33(cdk2) plays a unique role in cell cycle regulation of vertebrate cells.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Cdk2 Antibody Picoband® (monoclonal, 5B12D1) catalog # M00166-3. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.
Host	Mouse
Immunogen Region	E.coli-derived human Cdk2 recombinant protein (Position: E81-L298). Human Cdk2 shares 98.6% amino acid (aa) sequence identity with rat Cdk2.
Isotype	Mouse IgG2a
Molecular Weight	30 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Solute carrier family 2, facilitated glucose transporter member 1; Glucose transporter type 1, erythrocyte/brain; GLUT-1; HepG2 glucose transporter; SLC2A1; GLUT1
Tissue Specificity	Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P24941
Gene Id	1017
Gene Name	CDK2
Clone No	Clone: 5B12D1
Subcellular Location	Cell membrane. Multi-pass membrane protein. Melanosome.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	Flow Cytometry, IHC, WB
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Mouse<br>

Reference	1. Demetrick, D. J., Zhang, H., Beach, D. H.Chromosomal mapping of human CDK2, CDK4, and CDK5 cell cycle kinase genes.Cytogenet. Cell Genet. 66: 72-74, 1994.<br /><br />2. Tsai, L.-H., Harlow, E., Meyerson, M.Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated P33 kinase.Nature 353: 174-177, 1991.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004090-1	M00166-3	-	100 ug	$370		Add to Cart
BHA21004090-2	M00166-3-10ug	Sample	10 ug	$99		Add to Cart
BHA21004090-3	M00166-3-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004090-4	M00166-3-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004090-5	M00166-3-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004090-6	M00166-3-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004090-7	M00166-3-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004090-8	M00166-3-FITC	FITC	100 ug	$570		Add to Cart
BHA21004090-9	M00166-3-HRP	HRP	100 ug	$570		Add to Cart
BHA21004090-10	M00166-3-APC	APC	100 ug	$670		Add to Cart
BHA21004090-11	M00166-3-PE	PE	100 ug	$670		Add to Cart
BHA21004090-12	M00166-3-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004090-13	M00166-3-carrier-free	carrier-free	100 ug	$370		Add to Cart

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