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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD44 Picoband® Antibody (monoclonal, 7H7)

SKU : BHA21003142

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Mfr.No.	M00052-3, M00052-3-10ug, M00052-3-Biotin, M00052-3-Cy3, M00052-3-Dylight488, M00052-3-Dylight550, M00052-3-Dylight594, M00052-3-FITC, M00052-3-HRP, M00052-3-APC, M00052-3-PE, M00052-3-iFluor647, M00052-3-carrier-free
Alternative Names	signal transducer and activator of transcription 1, 91kDa
Background	CD44 is also known as LHR or MC56. The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alteative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alteative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-CD44 Picoband® Antibody (monoclonal, 7H7) catalog # M00052-3. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signali
Host	Mouse
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human CD44, different from the related mouse and rat sequences by two amino acids.
Isotype	Mouse IgG2b
Molecular Weight	82 kDa
Reactivity	Human, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Signal transducer and activator of transcription 1-alpha/beta; Transcription factor ISGF-3 components p91/p84; STAT1
Tissue Specificity	Expressed in several hair follicle cell types: basal and peripheral matrix cells, and cells of the outer and inner root sheaths. Expressed in colon. Present in cortical neurons (at protein level).
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Uniprot	P16070
Gene Id	960
Gene Name	CD44
Clone No	Clone: 7H7
Subcellular Location	Nucleus. Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, ICC, IF, Flow Cytometry
Description	Weste blot, 0.25-0.5ug/ml, Human, Rat<br> Immunocytochemistry/Immunofluorescence, 5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Fagan-Solis KD, et al. Challenging the roles of CD44 and lipolysis stimulated lipoprotein receptor in conveying Clostridium perfringens iota toxin cytotoxicity in breast cancer. Mol Cancer, 2014 Jul 2.<br /><br />2. Zhang P, et al. CD44 variant, but not standard CD44 isoforms, mediate disassembly of endothelial VE-cadherin junction on metastatic melanoma cells. FEBS Lett, 2014 Dec 20.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003142-1	M00052-3	-	100 ug	$370		Add to Cart
BHA21003142-2	M00052-3-10ug	Sample	10 ug	$99		Add to Cart
BHA21003142-3	M00052-3-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003142-4	M00052-3-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003142-5	M00052-3-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003142-6	M00052-3-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003142-7	M00052-3-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003142-8	M00052-3-FITC	FITC	100 ug	$570		Add to Cart
BHA21003142-9	M00052-3-HRP	HRP	100 ug	$570		Add to Cart
BHA21003142-10	M00052-3-APC	APC	100 ug	$670		Add to Cart
BHA21003142-11	M00052-3-PE	PE	100 ug	$670		Add to Cart
BHA21003142-12	M00052-3-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003142-13	M00052-3-carrier-free	carrier-free	100 ug	$370		Add to Cart

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