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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD40 antibody(DM101), Rabbit mAb

SKU : BHA18100273

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DIMA Biotechnology

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Mfr.No.	DME100101
Antigen	CD40
Background	This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the eXpression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial actIVation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessIVe hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatIVely spliced transcript variants of this gene encoding distinct isoforms have been reported.
Clonality	Monoclonal
Host	Rabbit
Isotype	Rabbit IgG
Reactivity	Human
Solubility	ELISA 1/5000-10000;Flow Cyt 1/100
Synonyms	CD40, Bp50, CDW40, MGC9013, TNFRSF5, p50
Usage	Research use only

Form	Powder
Purification	Purified from cell culture supernatant by affinity chromatography
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Applications	ELISA,Flow Cyt

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SKU	Supplier No.	Size	Your price	Quantity
BHA18100273	DME100101	100 ug	$398		Add to Cart
BHA18100273	DME100101	10 ug	$60		Add to Cart

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