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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD13/ANPEP Antibody Picoband® (monoclonal, 7F2)

SKU : BHA21003453

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Mfr.No.	M02591-5, M02591-5-10ug, M02591-5-Biotin, M02591-5-Cy3, M02591-5-Dylight488, M02591-5-Dylight550, M02591-5-Dylight594, M02591-5-FITC, M02591-5-HRP, M02591-5-APC, M02591-5-PE, M02591-5-iFluor647, M02591-5-carrier-free
Alternative Names	arylsulfatase A
Background	Membrane alanyl aminopeptidase (EC 3.4.11.2) also known as alanyl aminopeptidase (AAP) or aminopeptidase N (AP-N) is an enzyme that in humans is encoded by the ANPEP gene. It is mapped to 15q26.1. Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-CD13/ANPEP Antibody Picoband® (monoclonal, 7F2) catalog # M02591-5. Tested in IHC, WB applications. This antibody reacts with Human, Rat, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Hydrolyzes cerebroside sulfate.
Host	Mouse
Immunogen Region	E.coli-derived human CD13/ANPEP recombinant protein (Position: D148-S966).
Isotype	Mouse IgG1
Molecular Weight	150 kDa
Reactivity	Human, Rat, Monkey
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Arylsulfatase A; ASA; Cerebroside-sulfatase; Arylsulfatase A component B; Arylsulfatase A component C; ARSA
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P15144
Gene Id	290
Gene Name	ANPEP
Clone No	Clone: 7F2
Subcellular Location	Lysosome.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, IHC
Description	Weste blot, 0.25-0.5 ug/ml, Rat, Monkey<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human, Rat<br>

Reference	1. Delmas, B., Gelfi, J., L'Haridon, R., Vogel, L. K., Sjostrom, H., Noren, O., Laude, H. Aminopeptidase N is a major receptor for the enteropathogenic coronavirus TGEV. Nature 357: 417-420, 1992.<br /><br />2. Kruse, T. A., Bolund, L., Grzeschik, K.-H., Ropers, H. H., Olsen, J., Sjostrom, H., Noren, O. Assignment of the human aminopeptidase N (peptidase E) gene to chromosome 15q13-qter. FEBS Lett. 239: 305-308, 1988.<br /><br />3. Look, A. T., Ashmun, R. A., Shapiro, L. H., Peiper, S. C. Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N. J. Clin. Invest. 83: 1299-1307, 1989.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003453-1	M02591-5	-	100 ug	$370		Add to Cart
BHA21003453-2	M02591-5-10ug	Sample	10 ug	$99		Add to Cart
BHA21003453-3	M02591-5-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003453-4	M02591-5-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003453-5	M02591-5-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003453-6	M02591-5-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003453-7	M02591-5-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003453-8	M02591-5-FITC	FITC	100 ug	$570		Add to Cart
BHA21003453-9	M02591-5-HRP	HRP	100 ug	$570		Add to Cart
BHA21003453-10	M02591-5-APC	APC	100 ug	$670		Add to Cart
BHA21003453-11	M02591-5-PE	PE	100 ug	$670		Add to Cart
BHA21003453-12	M02591-5-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003453-13	M02591-5-carrier-free	carrier-free	100 ug	$370		Add to Cart

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