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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Cbx8 Antibody Picoband® (monoclonal, 8G7)

SKU : BHA21003237

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Mfr.No.	M05234, M05234-10ug, M05234-Biotin, M05234-Cy3, M05234-Dylight488, M05234-Dylight550, M05234-Dylight594, M05234-FITC, M05234-HRP, M05234-APC, M05234-PE, M05234-iFluor647, M05234-carrier-free
Alternative Names	protein kinase, AMP-activated, beta 2 non-catalytic subunit
Background	CBX8 functions as a transcriptional repressor and has a role in DNA damage response. This gene is mapped to chromosome 17q25.3 based on an alignment of the CBX8 sequence with the genomic sequence (GRCh38).
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Cbx8 Antibody Picoband® (monoclonal, 8G7) catalog # M05234. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways an
Host	Mouse
Immunogen Region	E.coli-derived human Cbx8 recombinant protein (Position: M1-R389).
Isotype	Mouse IgG2b
Molecular Weight	45 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	5'-AMP-activated protein kinase subunit beta-2; AMPK subunit beta-2; PRKAB2
Tissue Specificity	Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Uniprot	Q9HC52
Gene Id	57332
Gene Name	CBX8
Clone No	Clone: 8G7
Subcellular Location	Cytoplasm . Nucleus .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, Flow Cytometry
Description	Weste blot, 0.25-0.5ug/ml, Human<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Bardos, J. I., Saurin, A. J., Tissot, C., Duprez, E., Freemont, P. S. HPC3 is a new human Polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties. J. Biol. Chem. 275: 28785-28792, 2000. <br /><br />2. Oza, J., Ganguly, B., Kulkai, A., Ginjala, V., Yao, M., Ganesan, S. A novel role of chromodomain protein CBX8 in DNA damage response. J. Biol. Chem. 291: 22881-22893, 2016. Note: Erratum: J. Biol. Chem. 292: 761 only, 2017.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003237-1	M05234	-	100 ug	$370		Add to Cart
BHA21003237-2	M05234-10ug	Sample	10 ug	$99		Add to Cart
BHA21003237-3	M05234-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003237-4	M05234-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003237-5	M05234-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003237-6	M05234-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003237-7	M05234-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003237-8	M05234-FITC	FITC	100 ug	$570		Add to Cart
BHA21003237-9	M05234-HRP	HRP	100 ug	$570		Add to Cart
BHA21003237-10	M05234-APC	APC	100 ug	$670		Add to Cart
BHA21003237-11	M05234-PE	PE	100 ug	$670		Add to Cart
BHA21003237-12	M05234-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003237-13	M05234-carrier-free	carrier-free	100 ug	$370		Add to Cart

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