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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Calnexin/CANX Antibody Picoband® (monoclonal, 8D10B3)

SKU : BHA21004432

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Mfr.No.	M03372-2, M03372-2-10ug, M03372-2-Biotin, M03372-2-Cy3, M03372-2-Dylight488, M03372-2-Dylight550, M03372-2-Dylight594, M03372-2-FITC, M03372-2-HRP, M03372-2-APC, M03372-2-PE, M03372-2-iFluor647, M03372-2-carrier-free
Alternative Names	cadherin 3, type 1, P-cadherin (placental)
Background	Calnexin (CNX) is a 67 kDa integral protein of the endoplasmic reticulum. This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alteatively spliced transcript variants encoding different isoforms have been described.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Calnexin/CANX Antibody Picoband® (monoclonal, 8D10B3) catalog # M03372-2. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Host	Mouse
Immunogen Region	E.coli-derived human Calnexin/CANX recombinant protein (Position: E68-R582).
Isotype	Mouse IgG2b
Molecular Weight	95 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Cadherin-3; Placental cadherin; P-cadherin; CDH3; CDHP
Tissue Specificity	Expressed in some normal epithelial tissues and in some carcinoma cell lines.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P27824
Gene Id	821
Gene Name	CANX
Clone No	Clone: 8D10B3
Subcellular Location	Cell membrane. Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, IHC, ICC, IF, Flow Cytometry
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Denzel, A., Molinari, M., Trigueros, C., Martin, J. E., Velmurgan, S., Brown, S., Stamp, G., Owen, M. J. Early postnatal death and motor disorders in mice congenitally deficient in calnexin expression. Molec. Cell. Biol. 22: 7398-7404, 2002. <br /><br />2. Dickson, K. M., Bergeron, J. J. M., Shames, I., Colby, J., Nguyen, D. T., Chevet, E., Thomas, D. Y., Snipes, G. J. Association of calnexin with mutant peripheral myelin protein-22 ex vivo: a basis for 'gain-of-function' ER diseases. Proc. Nat. Acad. Sci. 99: 9852-9857, 2002.<br /><br />3. Gray, P. W., Byers, M. G., Eddy, R. L., Shows, T. B. The assignment of the calnexin gene to the q35 region of chromosome 5. (Abstract) Human Genome Mapping Workshop 93, Kobe, Japan 1993. P. 9.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004432-1	M03372-2	-	100 ug	$370		Add to Cart
BHA21004432-2	M03372-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21004432-3	M03372-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004432-4	M03372-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004432-5	M03372-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004432-6	M03372-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004432-7	M03372-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004432-8	M03372-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21004432-9	M03372-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21004432-10	M03372-2-APC	APC	100 ug	$670		Add to Cart
BHA21004432-11	M03372-2-PE	PE	100 ug	$670		Add to Cart
BHA21004432-12	M03372-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004432-13	M03372-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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