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Home / Primary Antibodies / Monoclonal Antibodies

Anti-ARA9/AIP Antibody Picoband® (monoclonal, 10G8)

SKU : BHA21002111

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Mfr.No.	M02759, M02759-10ug, M02759-Biotin, M02759-Cy3, M02759-Dylight488, M02759-Dylight550, M02759-Dylight594, M02759-FITC, M02759-HRP, M02759-APC, M02759-PE, M02759-iFluor647, M02759-carrier-free
Alternative Names	aryl hydrocarbon receptor interacting protein
Background	AIP, also known as, ARA9 or XAP-2, is a protein that in humans is encoded by the AIP gene. This gene is mapped to 11q13.2. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. AIP may play a positive role in aryl hydrocarbon receptor-mediated signalling possibly by influencing its receptivity for ligand and/or its nuclear targeting. It has been shown that AIP is the cellular negative regulator of the hepatitis B virus (HBV) X protein. AIP mutations may be the cause of a familial form of acromegaly, familial isolated pituitary adenoma (FIPA).
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-ARA9/AIP Antibody Picoband® (monoclonal, 10G8) catalog # M02759. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting. Cellular negative regulator of the hepatitis B virus (HBV) X protein.
Host	Mouse
Immunogen Region	E.coli-derived human ARA9 recombinant protein (Position: D91-H330). Human ARA9 shares 95% amino acid (aa) sequence identity with both mouse and rat ARA9.
Isotype	Mouse IgG2b
Molecular Weight	38 kDa
Reactivity	Human, Monkey, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	H receptor-interacting protein; AIP; Aryl-hydrocarbon receptor-interacting protein; HBV X-associated protein 2; XAP-2; Immunophilin homolog ARA9; AIP; XAP2
Tissue Specificity	Widely expressed. Higher levels seen in the heart, placenta and skeletal muscle. Not expressed in the liver.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	O00170
Gene Id	9049
Gene Name	AIP
Clone No	Clone: 10G8
Subcellular Location	Cytoplasm

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml<br> Immunocytochemistry/Immunofluorescence, 2ug/ml<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells<br>

Reference	1. Carver LA, Bradfield CA (April 1997). "Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo". J. Biol. Chem. 272(17): 114526.<br /><br />2. Kuzhandaivelu, N., Cong, Y.-S., Inouye, C., Yang, W.-M., Seto, E. XAP2, a novel hepatitis B virus X-associated protein that inhibits X transactivation. Nucleic Acids Res. 24: 4741-4750, 1996.<br /><br />3. Occhi G, Trivellin G, Ceccato F, et al. (2010). "Prevalence of AIP mutations in a large series of sporadic Italian acromegalic patients and evaluation of CDKN1B status in acromegalic patients with multiple endocrine neoplasia.". Eur. J. Endocrinol. 163 (3): 369376.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002111-1	M02759	-	100 ug	$370		Add to Cart
BHA21002111-2	M02759-10ug	Sample	10 ug	$99		Add to Cart
BHA21002111-3	M02759-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002111-4	M02759-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002111-5	M02759-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002111-6	M02759-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002111-7	M02759-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002111-8	M02759-FITC	FITC	100 ug	$570		Add to Cart
BHA21002111-9	M02759-HRP	HRP	100 ug	$570		Add to Cart
BHA21002111-10	M02759-APC	APC	100 ug	$670		Add to Cart
BHA21002111-11	M02759-PE	PE	100 ug	$670		Add to Cart
BHA21002111-12	M02759-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002111-13	M02759-carrier-free	carrier-free	100 ug	$370		Add to Cart

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