Mouse Anti-Human Ankyrin B Monoclonal IgG1

Mfr.No.	SMC-400, SMC-400D, SMC-400D-A390, SMC-400D-A488, SMC-400D-A594, SMC-400D-ALP, SMC-400D-APC, SMC-400D-BI, SMC-400D-FITC, SMC-400D-HRP, SMC-400D-PCP, SMC-400D-RPE, SMC-400S
Immunogen Species	Human
Alternative Names	ANK-2 Antibody, ANK2 Antibody, Ankyrin 2 Antibody, Ankyrin-2 Antibody, Ankyrin nonerythroid Antibody, Brain ankyrin Antibody, non-erythroid ankyrin Antibody, Ankyrin-B Antibody
Categories	Antibodies
Cellular Localization	Cytoskeleton, Cytoplasm, Myofibril, Sarcomere, M line, Apical Cell Membrane, Cell Membrane
Certificate Of Analysis	1 ug/ml of SMC-400 was sufficient for detection of Ankyrin-B in 20 ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Clonality	Monoclonal
Description	Mouse Anti-Human Ankyrin B Monoclonal IgG1
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Mouse
Gross Weight (kg)	1.4
Immunogen	Synthetic peptide amino acids 203-496 of human Ankyrin-B, Homo Sapiens (Human)
Immunogen Region	Synthetic peptide amino acids 203-496 of human Ankyrin-B
Isotype	IgG1
Launch Date	2012/04/24
Net Weight (g)	0.1
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Mouse, Rat, Human

Swissprot	Q01484
Accession Number	NP_001120965.1
Gene Id	287
Target	Ankyrin B
Clone No	S105-13
Research Area	Cell Markers, Neuron Markers, Membrane Markers, Neurotransmitter Receptors, Cell Signaling, Scaffold Proteins, Neuroscience

Buffer	PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration	1 mg/ml
Dilutions	WB (1:1000), IHC (1:200), ICC/IF (1:200); optimal dilutions for assays should be determined by the user.
Purification	Protein G Purified
Scientific Background	Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral membrane proteins. This linkage is required to maintain the integrity of the plasma membranes and to anchor specific ion channels, ion exchangers and ion transporters in the plasma membrane.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects ~200kDa. No cross reactivity against Ankyrin-G.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	IHC, WB, ICC/IF
Description	WB ; IHC ; ICC ; IF
Dilution	WB (1:1000), IHC (1:200), ICC/IF (1:200); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

Reference	1. Bennett V., Baines A.J. (2001) Physiol. Rev. 81 (3): 135392.

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11903507-1	SMC-400D	Unconjugated	100 ug	$330	Add to Cart
BHA11903507-2	SMC-400D-A390	ATTO 390	100 ug	$384	Add to Cart
BHA11903507-3	SMC-400D-A488	ATTO 488	100 ug	$383	Add to Cart
BHA11903507-4	SMC-400D-A594	ATTO 594	100 ug	$383	Add to Cart
BHA11903507-5	SMC-400D-ALP	Alkaline Phosphatase	100 ug	$376	Add to Cart
BHA11903507-6	SMC-400D-APC	APC	100 ug	$382	Add to Cart
BHA11903507-7	SMC-400D-BI	Biotin	100 ug	$378	Add to Cart
BHA11903507-8	SMC-400D-FITC	FITC	100 ug	$374	Add to Cart
BHA11903507-9	SMC-400D-HRP	HRP	100 ug	$370	Add to Cart
BHA11903507-10	SMC-400D-PCP	PerCP	100 ug	$382	Add to Cart
BHA11903507-11	SMC-400D-RPE	RPE	100 ug	$380	Add to Cart
BHA11903507-12	SMC-400S	Unconjugated	12 ug	$44	Add to Cart

Ankyrin B Antibody, Clone S105-13 - SMC-400