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Home / Primary Antibodies / Monoclonal Antibodies

AF647 Anti-Mouse CD45R/B220 Antibody[RA3.3A 1/6.1]

SKU : BHA10325536

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-F1112M
Background	CD45, also known as leukocyte common antigen (LCA), B220, and T200, is a 180-2CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is eessed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.40 kD single chain type I membrane glycoprotein. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 is one of the best negative selection markers for characterizing and/or isolating human mesenchymal stem cells from bone marrow and other sources. s.
Clonality	Monoclonal
Host	Rat
Immunogen	0
Isotype	Rat IgM, kappa
Reactivity	Mouse

Clone No	RA3.3A 1/6.1

Buffer	PBS with 0.05% Proclin300, 1% BSA
Storage	Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Applications	FCM

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA10325536	E-AB-F1112M	20Tests	$28		Add to Cart
BHA10325536	E-AB-F1112M	50Tests	$48		Add to Cart
BHA10325536	E-AB-F1112M	100Tests	$72		Add to Cart
BHA10325536	E-AB-F1112M	500Tests	$228		Add to Cart

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