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Home / Primary Antibodies / Monoclonal Antibodies

AF647 Anti-Human CD197/CCR7 Antibody[G043H7]

SKU : BHA10326018

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-F1159M
Background	CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity by affecting interactions between T cells and dendritic cells and their downstream effect. Nave T cells enter the lymph node through high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent. In addition, during immunological surveillance, B cells recirculate between B-cell-rich compartments (follicles or B cell zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to interact with T-helper cells; this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated with lymph node metastasis. Product Details
Clonality	Monoclonal
Host	Mouse
Immunogen	0
Isotype	Mouse IgG2a, kappa
Reactivity	Human

Clone No	G043H7
Research Area	Signal transduction, Cancer, Immunology

Buffer	PBS with 0.05% Proclin300, 1% BSA
Storage	Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Applications	FCM

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA10326018	E-AB-F1159M	20Tests	$90		Add to Cart
BHA10326018	E-AB-F1159M	50Tests	$135		Add to Cart
BHA10326018	E-AB-F1159M	100Tests	$189		Add to Cart
BHA10326018	E-AB-F1159M	200Tests	$325		Add to Cart

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