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Home / Primary Antibodies / Monoclonal Antibodies

AF488 Anti-Mouse CD162 Antibody[4RA10]

SKU : BHA10324894

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-F1034UL
Background	The 4RA10 antibody reacts with the N-terminal functional peptide of CD162 (P-selectin glycoprotein ligand-1, PSGL-1), encoded by the Selpl gene. PSGL-1 is expressed on the cell surface as a homodimer of approximately 230 kDa. In the mouse, Selpl mRNA is detected in most tissues, with high levels found in hematopoietic cells, brain, and adipose tissue. Flow cytometric analyses have revealed CD162 expression on bone marrow-derived mast and dendritic cells, splenic leukocytes, platelets, peripheral blood neutrophils, and neutrophil and T-cell lines. PSGL-1 is a ligand for P-selectin (CD62P) and is involved in leukocyte rolling, the migration of leukocytes into inflamed tissues, and responses to vascular injury. It is a sialomucin that must be specifically sialylated, fucosylated, and sulfated to bind P-selectin. There is also evidence that other ligands for PSGL-1 and CD62P may exist. 4RA10 mAb is reported to block the binding of mouse leukocytes to CD62P and CD62L.
Clonality	Monoclonal
Host	Rat
Immunogen	0
Isotype	Rat IgG1, kappa
Reactivity	Mouse

Clone No	4RA10

Buffer	PBS with 0.05% Proclin300, 1% BSA
Concentration	0.5 mg/mL
Storage	Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Applications	FCM

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA10324894	E-AB-F1034UL	25?g	$80		Add to Cart
BHA10324894	E-AB-F1034UL	50?g	$145		Add to Cart
BHA10324894	E-AB-F1034UL	100?g	$220		Add to Cart
BHA10324894	E-AB-F1034UL	200?g	$350		Add to Cart

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