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Home / Primary Antibodies / Monoclonal Antibodies

AF/LE Purified Anti-Human CD274/PD-L1 Antibody[29E.2A3]

SKU : BHA10325816

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-F11330
Background	CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-gamma production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
Clonality	Monoclonal
Host	Mouse
Immunogen	0
Isotype	Mouse IgG2b, kappa
Reactivity	Human

Clone No	29E.2A3
Research Area	Cancer, Immunology

Buffer	0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Concentration	0.5 mg/mL
Storage	Store at 2~8°C. Do not freeze.

Applications	Block, FA, FCM, IHC

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA10325816	E-AB-F11330	50?g	$95		Add to Cart
BHA10325816	E-AB-F11330	500?g	$395		Add to Cart
BHA10325816	E-AB-F11330	1mg	$595		Add to Cart

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