Mouse Anti-Acrolein conjugated protein Monoclonal IgG1

Mfr.No.	SMC-505, SMC-505D, SMC-505D-A390, SMC-505D-A488, SMC-505D-A594, SMC-505D-ALP, SMC-505D-APC, SMC-505D-BI, SMC-505D-FITC, SMC-505D-HRP, SMC-505D-PCP, SMC-505D-RPE, SMC-505S
Alternative Names	Acrolein modified protein Antibody, Acrolein conjugated protein Antibody, 2-Propen-1-one Antibody, 2-propenal Antibody, Acraldehyde Antibody, Acrolein Antibody, Acrylic aldehyde Antibody, Protein-bound Acrolein Antibody
Antigen	Acrolein
Categories	Antibodies
Certificate Of Analysis	A 1:1000 dilution of SMC-505 was sufficient for detection of Acrolein in 2 ug of Acrolein conjugated to BSA by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary Antibody.
Clonality	Monoclonal
Conjugate	Unconjugated, ATTO 390, ATTO 488, ATTO 594, Alkaline Phosphatase, APC, Biotin, FITC, HRP, PerCP, RPE
Description	Mouse Anti-Acrolein conjugated protein Monoclonal IgG1
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Mouse
Gross Weight (kg)	1.4
Immunogen	Synthetic Acrolein modified Keyhole Limpet Hemocyanin (KLH).
Immunogen Region	Synthetic Acrolein modified Keyhole Limpet Hemocyanin (KLH).
Isotype	IgG1
Launch Date	2017/03/23
Net Weight (g)	0.1
Reactivity	Species Independent
Recombinant	FALSE
Regulatory	RUO
Species Reactivity Medium	Species Independent

Target	Acrolein
Clone No	10A10
Research Area	Cancer, Oxidative Stress, Lipid peroxidation, Neurodegeneration, Alzheimer's Disease, Neuroscience

Buffer	PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide
Concentration	1 mg/ml
Dilutions	WB (1:1000); ICC/IF (1:50); FACS (1:50); FCM (1:50); ELISA (1:1000); optimal dilutions for assays should be determined by the user.
Purification	Protein G Purified
Scientific Background	Lipid peroxidation occurs when oxidizing agents attack carbon-carbon double bonds found in unsaturated lipids. In addition to membrane degradation, oxidation end-products have been found to damage cell viability through their mutagenic and toxic properties. These downstream functional consequences facilitate the development of disease and premature aging. Acrolein is an electrophilic conjugated aldehyde that is a terminal product of lipid peroxidation. Acrolein is highly mutagenic and reacts with nucleophilic functional groups in DNA and proteins such as cysteine, histidine, and lysine residues (1).
Shipping Temperature	Blue Ice or 4°C
Specificity	Specific for Acrolein modified proteins. Does not detect free acrolein. Does not cross-react with Crotonaldehyde, Hexanoyl Lysine, 4-Hydroxy-2-hexenal, 4-Hydroxy nonenal, Malondialdehyde, or Methylglyoxal modified proteins.
Storage	-20ºC
Storage Buffer	PBS pH 7.4, 50% glycerol, 0.09% Sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C
Trademark	MOLECULAR SIGNATURE

Applications	ELISA, FACS, WB, ICC/IF, FCM, IHC
Description	WB ; ICC ; IF ; FACS ; FCM ; ELISA
Dilution	WB (1:1000); ICC/IF (1:50); FACS (1:50); FCM (1:50); ELISA (1:1000); IHC (1:100); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

Reference	1. Takabe, W. et al. (2001) Carcinogenesis. 22 (6): 935-942

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11905388-1	SMC-505D	Unconjugated	100 ug	$409	Add to Cart
BHA11905388-2	SMC-505D-A390	ATTO 390	100 ug	$463	Add to Cart
BHA11905388-3	SMC-505D-A488	ATTO 488	100 ug	$462	Add to Cart
BHA11905388-4	SMC-505D-A594	ATTO 594	100 ug	$462	Add to Cart
BHA11905388-5	SMC-505D-ALP	Alkaline Phosphatase	100 ug	$455	Add to Cart
BHA11905388-6	SMC-505D-APC	APC	100 ug	$461	Add to Cart
BHA11905388-7	SMC-505D-BI	Biotin	100 ug	$458	Add to Cart
BHA11905388-8	SMC-505D-FITC	FITC	100 ug	$453	Add to Cart
BHA11905388-9	SMC-505D-HRP	HRP	100 ug	$449	Add to Cart
BHA11905388-10	SMC-505D-PCP	PerCP	100 ug	$461	Add to Cart
BHA11905388-11	SMC-505D-RPE	RPE	100 ug	$459	Add to Cart
BHA11905388-12	SMC-505S	Unconjugated	12 ug	$44	Add to Cart

Acrolein Antibody, Clone 10A10 - SMC-505