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Home / VECTOR &VIRUS / Lentivirus

RUNX1 Reporter Lentivirus

SKU : BHV19400078

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Mfr.No.	LTV-0085, LTV-0085-1S, LTV-0085-2S, LTV-0085-3S, LTV-0085-4S, LTV-0085-5S, LTV-0085-6S, LTV-0085-15S, LTV-0085-16S
Description	RUNX1 Reporter Lentivirus: High-quality, lentiviral transcription factor (TF) reporter system that provides a sensitive fluorescent or luminescent readout for human/mouse RUNX family transcription factor 1 (RUNX1) transcriptional activity in mammalian cells. The RUNX1 reporter is constructed with tandem repeats of consensus RUNX1 DNA binding elements to read out its transcriptional activity. As a member of the core-binding factor family of transcription factors, RUNX1, also known as acute myeloid leukemia 1 protein (AML1), modulates cell proliferation, differentiation, and survival. RUNX1 plays an indispensable role in definitive hematopoiesis and hematological malignancies and as an emerging therapeutic target in cardiovascular disease. The reporter lentivirus is purified by PEG precipitation and sucrose gradient centrifugation, and is ideal for studying RUNX1 transcriptional activity in difficult-to-transfect cells including primary and/or thawed cells.
Serotype	VSV-G
Reporter	Firefly Luc, RFP, BFP2, GFP
Response Element	RUNX1 response element
Selection	Blasticidin, Puromycin
Signaling pathway	RUNX1 Signaling Pathway
Species	Human/mouse
Applications Range	Monitor transcriptional activity of RUNX1 in mammalian cells, screen for activators or inhibitors of RUNX1 transcriptional activity. The fluorescent reporter enables convenient readout using flow cytometry, fluorescence microscopy, etc.
Virus Type	TF Reporter Lentivirus

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Combination SKU	Supplier No.	Amount (TU)	Selection	Reporter	Your price	Quantity
BHV19400078-1	LTV-0085-1S	5x10^6	Puromycin	GFP	$595		Add to Cart
BHV19400078-2	LTV-0085-2S	5x10^6	Blasticidin	RFP	$595		Add to Cart
BHV19400078-3	LTV-0085-3S	2x10^6	Puromycin	Firefly Luc	$595		Add to Cart
BHV19400078-4	LTV-0085-4S	2x10^6	Blasticidin	Firefly Luc	$595		Add to Cart
BHV19400078-5	LTV-0085-5S	5x10^6	Blasticidin	GFP	$595		Add to Cart
BHV19400078-6	LTV-0085-6S	5x10^6	Puromycin	RFP	$595		Add to Cart
BHV19400078-7	LTV-0085-15S	5x10^6	Puromycin	BFP2	$595		Add to Cart
BHV19400078-8	LTV-0085-16S	5x10^6	Blasticidin	BFP2	$595		Add to Cart

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