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Home / VECTOR &VIRUS / Lentivirus

NKX2.5 Reporter Lentivirus

SKU : BHV19400080

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Mfr.No.	LTV-0087, LTV-0087-1S, LTV-0087-2S, LTV-0087-3S, LTV-0087-4S, LTV-0087-5S, LTV-0087-6S, LTV-0087-15S, LTV-0087-16S
Description	NKX2.5 Reporter Lentivirus: High-quality, lentiviral transcription factor (TF) reporter system that provides a sensitive fluorescent or luminescent readout for human/mouse NK2 homeobox 5 (NKX2.5) transcriptional activity in mammalian cells. The NKX2.5 reporter is constructed with tandem repeats of consensus NKX2.5 responsive elements to read out its transcriptional activity. As a critical component of the cardiac gene regulatory network, NKX2.5 guides cardiac lineage formation and may help myocytes endure cytotoxic stress. In humans, proper NKX2.5 expression is essential for the development of atrial, ventricular, and conotruncal septation. Loss of function mutations of NKX2.5 are associated with congenital heart disease and related ailments. Mutations in this gene can also cause congenital hypothyroidism. The reporter lentivirus is purified by PEG precipitation and sucrose gradient centrifugation, and is ideal for studying NKX2.5 transcriptional activity in difficult-to-transfect cells including primary and/or thawed cells.
Serotype	VSV-G
Reporter	Firefly Luc, RFP, BFP2, GFP
Response Element	NKX2.5 response element
Selection	Blasticidin, Puromycin
Signaling pathway	NKX2.5 Signaling Pathway
Species	Human/mouse
Applications Range	Monitor transcriptional activity of NKX2.5 in mammalian cells, screen for activators or inhibitors of NKX2.5 transcriptional activity. The fluorescent reporter enables convenient readout using flow cytometry, fluorescence microscopy, etc.
Virus Type	TF Reporter Lentivirus

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Combination SKU	Supplier No.	Amount (TU)	Selection	Reporter	Your price	Quantity
BHV19400080-1	LTV-0087-1S	5x10^6	Puromycin	GFP	$595		Add to Cart
BHV19400080-2	LTV-0087-2S	5x10^6	Blasticidin	RFP	$595		Add to Cart
BHV19400080-3	LTV-0087-3S	2x10^6	Puromycin	Firefly Luc	$595		Add to Cart
BHV19400080-4	LTV-0087-4S	2x10^6	Blasticidin	Firefly Luc	$595		Add to Cart
BHV19400080-5	LTV-0087-5S	5x10^6	Blasticidin	GFP	$595		Add to Cart
BHV19400080-6	LTV-0087-6S	5x10^6	Puromycin	RFP	$595		Add to Cart
BHV19400080-7	LTV-0087-15S	5x10^6	Puromycin	BFP2	$595		Add to Cart
BHV19400080-8	LTV-0087-16S	5x10^6	Blasticidin	BFP2	$595		Add to Cart

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