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Home / VECTOR &VIRUS / Lentivirus

NFE2 Reporter Lentivirus

SKU : BHV19400064

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Mfr.No.	LTV-0069, LTV-0069-1S, LTV-0069-2S, LTV-0069-3S, LTV-0069-4S, LTV-0069-5S, LTV-0069-6S
Description	NFE2 Reporter Lentivirus: High-quality, lentiviral transcription factor (TF) reporter system that provides a sensitive fluorescent or luminescent readout for human/mouse Nuclear factor, erythroid 2 (NFE2, 45 kDa subunit) activity in mammalian cells. NFE2 is essential for regulating erythroid and megakaryocytic maturation and differentiation, including platelet production, megakaryocyte biogenesis, and erythroid cell function. The NFE2 protein forms heterodimers with small MAF proteins such as MAF-G to regulate gene transcription. The NFE2 reporter lentivirus contains consensus NFE2 DNA-binding elements from the PBGD promoter to read out transcriptional activity of NFE2. The reporter lentivirus is purified by PEG precipitation and sucrose gradient centrifugation, and is ideal for studying NFE2 activity in difficult-to-transfect cells including primary and/or thawed cells.
Promoter	EF1a
Serotype	VSV-G
Reporter	Firefly Luc, RFP, GFP
Response Element	NFE2 DNA-binding elements (from the PBGD promoter)
Selection	Blasticidin, Puromycin
Signaling pathway	NFE2 pathway
Species	Human/mouse
Applications Range	Monitor NFE2 transcriptional activity in mammalian cells, screen for activators or inhibitors of NFE2 signaling. The fluorescent reporter enables convenient readout using flow cytometry, fluorescence microscopy, etc. NFE2 is essential for regulating erythroid and megakaryocytic maturation and differentiation, including platelet production, megakaryocyte biogenesis, and erythroid cell function. The NFE2 protein forms heterodimers with small MAF proteins such as MAF-G to regulate gene transcription. The NFE2 reporter lentivirus contains consensus NFE2 DNA-binding elements from the PBGD promoter to read out transcriptional activity of NFE2.
Virus Type	TF Reporter Lentivirus

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Combination SKU	Supplier No.	Amount (TU)	Selection	Reporter	Promoter	Your price	Quantity
BHV19400064-1	LTV-0069-1S	5x10^6	Puromycin	GFP	EF1a	$595		Add to Cart
BHV19400064-2	LTV-0069-2S	5x10^6	Blasticidin	RFP	EF1a	$595		Add to Cart
BHV19400064-3	LTV-0069-3S	2x10^6	Puromycin	Firefly Luc	EF1a	$595		Add to Cart
BHV19400064-4	LTV-0069-4S	2x10^6	Blasticidin	Firefly Luc	EF1a	$595		Add to Cart
BHV19400064-5	LTV-0069-5S	5x10^6	Blasticidin	GFP	EF1a	$595		Add to Cart
BHV19400064-6	LTV-0069-6S	5x10^6	Puromycin	RFP	EF1a	$595		Add to Cart

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