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Home / VECTOR &VIRUS / Lentivirus

GATA3 Reporter Lentivirus

SKU : BHV19400072

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Mfr.No.	LTV-0077, LTV-0077-1S, LTV-0077-2S, LTV-0077-3S, LTV-0077-4S, LTV-0077-5S, LTV-0077-6S, LTV-0077-1S-1, LTV-0077-2S-1, LTV-0077-3S-1, LTV-0077-4S-1, LTV-0077-5S-1, LTV-0077-6S-1, LTV-0077-1S-1-1-1, LTV-0077-2S-1-1-1, LTV-0077-3S-1-1-1, LTV-0077-4S-1-1-1, L
Description	GATA3 Reporter Lentivirus: High-quality, lentiviral transcription factor (TF) reporter system that provides a sensitive fluorescent or luminescent readout for human/mouse GATA3 transcriptional activity in mammalian cells. The GATA3 Reporter Lentivirus is constructed with tandem repeats of the consensus GATA3 DNA-binding elements which is transcriptionally responsive to the transcription factor GATA3. GATA3 plays an essential role in the transcriptional control of Th2 cell differentiation and T lymphoid development and immune regulation. GATA3 is also expressed in multipotent hematopoietic stem cells and regulates the balance between self-renewal and differentiation. GATA proteins GATA1,2,3 have overlapping but distinct sequence preferences for DNA binding affinity. For example, GATA2 has been shown to bind the GATA3 binding motif which can only be poorly bound by GATA1. GATA1 and GATA2 play essential roles in the development and maintenance of the erythroid and megakaryocytic lineage, and the proliferation and survival of early hematopoietic cells, respectively. The reporter lentivirus is purified by PEG precipitation and sucrose gradient centrifugation, and is ideal for studying GATA3 transcriptional activity in difficult-to-transfect cells including primary and/or thawed cells.
Promoter	EF1a
Serotype	VSV-G
Reporter	Firefly Luc, RFP, GFP
Response Element	GATA3 response element
Selection	Blasticidin, Puromycin
Signaling pathway	GATA3 Signaling Pathway
Species	Human/mouse
Applications Range	Monitor transcriptional activity of GATA3 in mammalian cells, screen for activators or inhibitors of GATA3 transcriptional activity. The fluorescent reporter enables convenient readout using flow cytometry, fluorescence microscopy, etc. The GATA3 Reporter Lentivirus is constructed with tandem repeats of the consensus GATA3 DNA-binding elements which is transcriptionally responsive to the transcription factor GATA3. GATA3 plays an essential role in the transcriptional control of Th2 cell differentiation and T lymphoid development and immune regulation. GATA3 is also expressed in multipotent hematopoietic stem cells and regulates the balance between self-renewal and differentiation. GATA proteins GATA1,2,3 have overlapping but distinct sequence preferences for DNA binding affinity. For example, GATA2 has been shown to bind the GATA3 binding motif which can only be poorly bound by GATA1. GATA1 and GATA2 play essential roles in the development and maintenance of the erythroid and megakaryocytic lineage, and the proliferation and survival of early hematopoietic cells, respectively.
Virus Type	TF Reporter Lentivirus

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Combination SKU	Supplier No.	Amount (TU)	Selection	Reporter	Promoter	Your price	Quantity
BHV19400072-1	LTV-0077-1S	5x10^6	Puromycin	GFP	EF1a	$595		Add to Cart
BHV19400072-2	LTV-0077-2S	5x10^6	Blasticidin	RFP	EF1a	$595		Add to Cart
BHV19400072-3	LTV-0077-3S	2x10^6	Puromycin	Firefly Luc	EF1a	$595		Add to Cart
BHV19400072-4	LTV-0077-4S	2x10^6	Blasticidin	Firefly Luc	EF1a	$595		Add to Cart
BHV19400072-5	LTV-0077-5S	5x10^6	Blasticidin	GFP	EF1a	$595		Add to Cart
BHV19400072-6	LTV-0077-6S	5x10^6	Puromycin	RFP	EF1a	$595		Add to Cart
BHV19400072-7	LTV-0077-1S-1	5x10^6	Puromycin	GFP	EF1a	$595		Add to Cart
BHV19400072-8	LTV-0077-2S-1	5x10^6	Blasticidin	RFP	EF1a	$595		Add to Cart
BHV19400072-9	LTV-0077-3S-1	2x10^6	Puromycin	Firefly Luc	EF1a	$595		Add to Cart
BHV19400072-10	LTV-0077-4S-1	2x10^6	Blasticidin	Firefly Luc	EF1a	$595		Add to Cart
BHV19400072-11	LTV-0077-5S-1	5x10^6	Blasticidin	GFP	EF1a	$595		Add to Cart
BHV19400072-12	LTV-0077-6S-1	5x10^6	Puromycin	RFP	EF1a	$595		Add to Cart
BHV19400072-13	LTV-0077-1S-1-1-1	5x10^6	Puromycin	GFP	EF1a	$595		Add to Cart
BHV19400072-14	LTV-0077-2S-1-1-1	5x10^6	Blasticidin	RFP	EF1a	$595		Add to Cart
BHV19400072-15	LTV-0077-3S-1-1-1	2x10^6	Puromycin	Firefly Luc	EF1a	$595		Add to Cart
BHV19400072-16	LTV-0077-4S-1-1-1	2x10^6	Blasticidin	Firefly Luc	EF1a	$595		Add to Cart
BHV19400072-17	LTV-0077-5S-1-1-1	5x10^6	Blasticidin	GFP	EF1a	$595		Add to Cart
BHV19400072-18	LTV-0077-6S-1-1-1	5x10^6	Puromycin	RFP	EF1a	$595		Add to Cart

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