JAK2-IN-6

Mfr.No.	T40443
Description	JAK2-IN-6, a polysubstituted aminothiazole derivative, is a potent and selective inhibitor of JAK2 (ic50 at 22.86 ug/mL). Jak2-in-6 inhibits the activity of JAK2 enzymes by interfering with Jak2-related signaling pathways, thereby producing therapeutic effects on the specific disease IN which JAK2 is dysregulated, and does not show activity on JAK1 and JAK3. JAK2 is a protein involved in signaling pathways that regulate cell growth and division. Abnormal activation of JAK2 has been linked to a variety of diseases, including some types of cancer and inflammatory diseases. JAK2-IN-6 has antiproliferative activity against cancer cells.
Molecular Formula	C14H10ClN3OS2
Signaling Pathways	Angiogenesis, Chromatin/Epigenetic, JAK/STAT signaling, Stem Cells
Smiles	C(=O)(C=1SC(NC2=CC=CC=C2)=NC1N)C3=CC=C(Cl)S3
Cas Number	353512-04-6
Molecular Weight	335.83
Target	JAK

Have you used this product?

SKU	Supplier No.	Size	Your price
BHB20428489	T40443	1 mg	$39	Add to Cart
BHB20428489	T40443	5 mg	$89	Add to Cart
BHB20428489	T40443	10 mg	$128	Add to Cart
BHB20428489	T40443	25 mg	$219	Add to Cart
BHB20428489	T40443	50 mg	$326	Add to Cart
BHB20428489	T40443	100 mg	$486	Add to Cart
BHB20428489	T40443	500 mg	$1060	Add to Cart